Invitrogen™ Dynabeads™ M-270 Carboxylic Acid Magnetic Beads

Invitrogen™ Dynabeads™ M-270 Carboxylic Acid are uniform, superparamagnetic microspheres designed for efficient covalent immobilization of proteins, peptides, antibodies, and other biomolecules. These hydrophilic beads feature carboxylic acid surface groups, enabling stable amide bond formation with primary amino or sulfhydryl groups using carbodiimide-mediated coupling chemistry.

With a diameter of 2.8 µm, Dynabeads™ M-270 provide optimal surface area, excellent suspension stability, and efficient magnetic separation. Their highly controlled surface chemistry ensures reliable immobilization while minimizing nonspecific binding, making them ideal for sensitive downstream applications in protein purification, immunoassays, and molecular biology workflows.

These research-grade magnetic beads offer rapid and gentle coupling at neutral to low pH and low temperatures, preserving the biological activity of sensitive proteins and peptides. Their high bead concentration and uniform size distribution enable consistent performance and reproducible experimental results, including high-throughput applications.

Key Features and Benefits

• Hydrophilic magnetic beads with carboxylic acid surface functionality
• Enables covalent coupling of proteins, peptides, and biomolecules
• Compatible with carbodiimide crosslinking chemistry (EDC/NHS)
• Uniform bead size (2.8 µm) ensures reproducible performance
• Low nonspecific binding to nucleic acids and biomolecules
• Gentle immobilization preserves biological activity
• Rapid magnetic separation for efficient workflows
• Suitable for manual and automated high-throughput applications

Applications

• Protein and peptide immobilization
• Antibody coupling and immunoassay development
• Protein purification and isolation
• Biomolecule capture and separation
• Affinity purification workflows
• Biosensor and assay development
• Molecular biology and biotechnology research
• Magnetic separation of biological targets

Technical Specifications

Ordering Information

Invitrogen Dynabeads M-270 Carboxylic Acid provide a reliable and efficient solution for biomolecule immobilization and magnetic separation. Their uniform size, hydrophilic surface, and stable covalent coupling capability make them ideal for protein purification, immunoassays, and molecular biology applications. These high-performance magnetic beads are trusted tools for researchers requiring precise, reproducible, and efficient magnetic separation and conjugation workflows.