Apollo Sci. 6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC)

High-Purity Derivatization Reagent for Amino Acid and Peptide Analysis

6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) is a fluorescent derivatization reagent used extensively in amino acid analysis by pre-column derivatization, particularly in HPLC and UPLC workflows. AQC reacts efficiently with primary and secondary amines to form stable, highly fluorescent derivatives, making it ideal for detecting free amino acids, peptides, and amines in complex biological samples.

AQC enables sensitive and selective quantification with fluorescence detection (FLD) or mass spectrometry (MS). It is widely used in bioanalytical, clinical, pharmaceutical, and nutritional science research.

✅ Key Features & Benefits

• High Reactivity – Forms stable derivatives with both primary and secondary amines
• Fluorescent Labeling Agent – Ideal for sensitive detection in HPLC and UPLC workflows
• Stable Derivatized Products – Suitable for automated or high-throughput analysis
• Multiple Pack Sizes Available – 100 mg, 500 mg, and 1 g bottles for research or production scale
• Widely Cited Reagent – Trusted for quantitative amino acid profiling

🧪 Applications

• Pre-column derivatization of amino acids for HPLC/UPLC-FLD or UPLC-MS/MS
• Peptide and protein hydrolysate analysis
• Metabolomics and nutritional analysis
• Biological fluid profiling (e.g., plasma, serum, urine)
• Quantification of amino acids in pharmaceuticals and food matrices

🔧 Technical Specifications

Apollo Scientific’s 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate (AQC) is a reliable and essential derivatization reagent for fluorescence-based amino acid detection and quantification. Its reactivity, stability, and compatibility with modern analytical systems make it a preferred choice for researchers conducting bioanalytical, clinical, and nutritional assays.