Specifications:
Application | Cell culture, Microbiology, molecular biology | ||
Storage Temperature | Ambient | ||
Product Type | Laboratory Chemical | Forms | Powder |
Product Brand | VWR | ||
Product Grade | Analytical grade | Formula | C₁₅H₂₃NO₄ |
High-Purity Protein Synthesis Inhibitor for Eukaryotic Cell Research
VWR Cycloheximide is a potent eukaryotic translation inhibitor derived from Streptomyces griseus, widely used in molecular biology, biochemistry, and microbiology research. With a minimum purity of 90.0%, it reliably inhibits protein biosynthesis at the elongation step during translation, making it indispensable for protein turnover studies, apoptosis assays, and antifungal selection protocols.
Key Features
- High-Quality Research Grade – ≥90.0% purity for experimental reproducibility
- Reversible Action – Protein synthesis inhibition is rapidly reversible upon removal
- Cell-Type Specific Effects – Can both induce or inhibit apoptosis depending on context
- Selective Agent – Ideal for yeast and fungal growth control
- Versatile Applications – Suitable for cycloheximide chase experiments, protein half-life analysis, and more
Specifications
Property | Value |
---|---|
Chemical Name | Cycloheximide |
Synonym | Actidione |
CAS Number | 66-81-9 |
Molecular Formula | C₁₅H₂₃NO₄ |
Molar Mass | 281.35 g/mol |
Purity | ≥90.0% |
Hazard Classification | GHS06, GHS08, GHS09 |
ADR Classification | Class 6.1, PG I |
UN Number | 2811 |
Storage Temperature | Ambient |
Handling Note | Use only in restricted-access labs |
Applications
- Protein Synthesis Inhibition – Translation blocking in yeast and mammalian cells
- Apoptosis Research – Cell-type specific apoptosis modulation
- Cycloheximide Chase Assays – For determining protein half-lives
- Fungal Suppression – Used to inhibit growth of yeast and fungi in selective media
- Short-lived Protein Detection – For studying transient protein expression
Activity Spectrum
Effective against eukaryotic organisms, particularly:
- Candida spp.
- Aspergillus spp.
- Saccharomyces spp.
- Penicillium spp.
Ordering Information
Catalog Number | Pack Size | Packaging Type |
---|---|---|
441892A | 1 g | Glass bottle |
441894C | 10 g | Glass bottle |
VWR® Cycloheximide ≥90% is a gold-standard tool in cell biology and biochemical research, offering precise control over protein translation, fungal growth suppression, and apoptotic pathways. It is essential for laboratories focused on gene expression regulation, protein stability studies, and eukaryotic cell manipulation.
- Pack Size: 1g 10g