Thermo Scientific™ Zeba™ Spin Desalting 96-well Filter Plate, 7K MWCO

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Specifications:
Application Size Exclusion Chromatography
Storage Temperature 2-8°C
Product Type columns
Product Brand Thermo Fisher Scientific™
Product Grade Molecular Biology

The Thermo Scientific™ Zeba™ Spin Desalting 96-well Filter Plates are high-throughput, ready-to-use devices designed for rapid and efficient desalting, buffer exchange, and removal of low molecular weight contaminants from protein and biological samples. Each plate contains a proprietary size-exclusion resin with a 7K molecular weight cut-off (MWCO), offering exceptional performance for small-volume sample cleanup prior to downstream applications such as mass spectrometry, HPLC, ELISA, metabolite analysis, and assay development.

With ≥95% removal of salts, dyes, biotin, and other small molecules (<1,000 Da), these filter plates enable robust sample preparation without the need for tedious column equilibration or resin dispensing. The plates are fully compatible with manual or automated centrifuge workflows and require just five minutes to process 96 samples simultaneously.

Key Features & Benefits

  • High Recovery & Minimal Sample Loss
    Proprietary low-binding resin ensures maximal protein recovery and reproducibility.
  • Fast & Convenient Workflow
    Complete sample processing in <5 minutes; no need for fraction collection or gravity flow.
  • High-Throughput Format
    Designed to process 96 samples at once, ideal for screening and analytical workflows.
  • Reliable Desalting Performance
    Removes >95% of salts, dyes, and labeling reagents such as biotin or fluorophores.
  • Ready-to-Use
    Pre-filled, pre-packed plates require no hydration or resin packing—ready out of the box.
  • MWCO 7K
    Effectively retains proteins and biomolecules ≥7,000 Da while allowing smaller molecules to pass through.

Applications

  • Mass spectrometry (LC-MS/MS) sample cleanup
  • Protein buffer exchange for downstream assays
  • Removal of excess labeling reagents (e.g., biotin, dyes)
  • Preparation of protein samples for HPLC or capillary electrophoresis
  • Rapid desalting in ELISA and functional assays

Technical Specifications

AttributeDetails
Product TypeSpin Desalting Plate
Format96-well Filter Plate
MWCO7,000 Da
Resin TypeProprietary size-exclusion chromatography
Sample Volume20–100 μL per well
ThroughputUp to 96 samples simultaneously
Purification TargetProtein, buffer exchange
Storage ConditionStore at 4°C
Unit Sizes Available2 plates (Cat. No. 89807), 4 plates (89808)


The Zeba™ 96-well Spin Desalting Filter Plates (7K MWCO) provide a high-performance solution for rapid protein desalting and cleanup in parallel format. Whether preparing samples for LC-MS, removing buffer salts, or conducting assay development, these filter plates offer a fast, reproducible, and scalable method for processing up to 96 samples in minutes—ideal for modern proteomics and biochemical workflows.

  • Pack Size:   2/pk 4/pk

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