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Thermo Scientific™ Pierce™ Sodium Dodecyl Sulfate (SDS), Lauryl
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Specifications:
| Application | Protein Electrophoresis & Western Blotting | ||
| Storage Temperature | Ambient | ||
| Product Type | Molecular Biology Reagent | Forms | Powder |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Molecular Biology | Formula | CH₃(CH₂)₁₁OSO₃Na |
Standard-Grade Anionic Detergent for Protein Electrophoresis and Cell Lysis Applications
Thermo Scientific™ Sodium Dodecyl Sulfate (SDS), Lauryl is a standard-grade anionic detergent widely used for protein denaturation, polyacrylamide gel electrophoresis (PAGE), and membrane disruption in molecular biology workflows. Formulated as a mixture of linear alkyl sulfate chains (primarily C12, with minor C10–C18), this SDS is especially suited for denaturing protein electrophoresis (SDS-PAGE) and preparation of cell lysis buffers.
Its amphipathic properties allow it to disrupt non-covalent interactions in proteins, providing uniform negative charge and linearization of protein structures, essential for molecular weight determination by PAGE. This lauryl-grade SDS offers consistent performance for routine lab protocols where ultra-purity is not required.
Key Features & Benefits
- Effective Protein Denaturant – Essential for accurate molecular weight estimation in SDS-PAGE
- Formulated for Routine Use – Cost-effective and reliable for everyday protein and cell lysis protocols
- Mixed Chain Lengths – C12 dominant (≥60%) with C14, C16, C10, and C18 fractions for broader performance range
- High Solubility – Forms clear 10% (w/v) aqueous solution with minimal particulate matter
- Thermally Stable – Cloud point exceeds 100°C, ensuring stable performance at elevated temperatures
- Available in Multiple Sizes – Offered in 100 g and 1 kg formats for flexibility in lab-scale or bulk usage
Applications
- SDS-PAGE – Denaturing electrophoresis of proteins based on size
- Protein Sample Preparation – Facilitates unfolding and solubilization of complex protein structures
- Cell and Tissue Lysis – Common component in lysis buffers for protein and nucleic acid extraction
- Biochemical Assays – Used in enzyme inactivation, protein modification, and solubilization protocols
- Routine Molecular Biology – Suitable for teaching, research, and standard lab testing applications
Technical Specifications
| Attribute | Specification |
|---|---|
| Product Name | Sodium Dodecyl Sulfate (Lauryl) |
| Catalog Numbers | 28364 (100 g), 28365 (1 kg) |
| Chemical Type | Anionic detergent (Alkyl sulfate mixture) |
| Form | White powder |
| Solubility | 10% (w/v) aqueous solution must be clear, colorless to yellow |
| Chain Length Distribution | C12 ≥60%, C14 = 20–35%, C16 <10%, C10/C18 <1% |
| Molecular Weight (C12) | 288.5 g/mol |
| CMC (C12-based) | 6–8 mM (0.1728–0.2304% w/v) |
| Aggregation Number | ~62 |
| Micelle Molecular Weight | ~18,000 g/mol |
| Cloud Point | >100°C |
| Dialyzable | No |
| Reagent Type | Detergent (Standard-grade) |
| Unit Sizes | 100 g, 1 kg |
| Regulatory Use | For Research Use Only |
Storage & Handling
- Store in original container in a cool, dry, and well-ventilated area (20°C to 25°C)
- Protect from direct sunlight and moisture
- Handle with gloves and eye protection to avoid skin/eye irritation
- SDS is harmful if inhaled or ingested; follow institutional chemical safety protocols
Thermo Scientific™ SDS (Lauryl) provides a dependable, cost-effective solution for laboratories performing routine protein electrophoresis, cell lysis, and sample preparation. With its mixed-chain composition and reliable performance, it is a practical detergent choice for both teaching and research laboratories that require consistency without the added cost of ultra-high purity.
- Pack Size: 1kg 100g