Thermo Scientific™ Linezolid 98%

Linezolid is a synthetic oxazolidinone antibiotic used to inhibit bacterial growth by targeting protein synthesis. It is particularly effective against gram-positive bacteria, including multidrug-resistant strains such as MRSA and VRE. It works by binding to the bacterial 50S ribosome, preventing the formation of the 70S initiation complex essential for protein synthesis.

Key Features:

1. Antibacterial Mechanism:
   • Inhibits bacterial translation by targeting the 50S ribosomal subunit.
   • Effective against resistant bacterial strains.
2. Purity and Quality:
   • Purity of ≥97.5% as determined by HPLC.
   • Supplied as a white to off-white powder.
3. Chemical Properties:
   • Formula: C₁₆H₂₀FN₃O₄
   • Molecular Weight: 337.4 g/mol
   • Melting Point: 181–183 °C
4. Applications:
   • Used in research on antibiotic resistance mechanisms.
   • Pharmaceutical studies and antibacterial drug development.

Specifications:

Applications:

1. Antibacterial Research:
   • Study mechanisms of action and resistance in gram-positive bacteria.
2. Pharmaceutical Development:
   • Development of novel antibacterial agents targeting multidrug-resistant strains.
3. Clinical Microbiology:
   • Exploration of linezolid's role in treating resistant infections such as MRSA and VRE.
4. Drug-Target Interaction Studies:
   • Investigate the binding of linezolid to bacterial ribosomes.

Advantages:

• High Purity: Ensures reliable performance in research and development.
• Wide Spectrum Activity: Effective against a broad range of gram-positive pathogens.
• Stability: Stable under ambient storage conditions.

Storage and Handling:

• Storage Conditions: Store at ambient temperature in a dry environment to maintain stability.
• Handling Precautions:
  • Handle with appropriate personal protective equipment (PPE).
  • Avoid inhalation, ingestion, or direct contact with the skin or eyes.

Safety Information:

• Warning: May pose health risks if not handled correctly. Use in compliance with safety protocols.

The Thermo Scientific Linezolid (98%) is a high-purity antibiotic essential for antibacterial research and pharmaceutical development. Its specificity for gram-positive pathogens and reliable performance make it an indispensable tool for studies addressing antibiotic resistance and drug efficacy.