Thermo Scientific™ Doxycycline hyclate 97%

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Specifications:
Application Cell culture, Analytical Chemistry
Storage Temperature 2-8°C
Product Type Antibiotic Forms Powder
Product Brand Thermo Fisher Scientific™, thermo Scientific
Product Grade Analytical grade Formula C₂₂H₂₄N₂O₈·HCl·0.5H₂O·0.5C₂H₆

Doxycycline hyclate is a semi-synthetic broad-spectrum tetracycline antibiotic used extensively in microbiology, pharmacology, and biomedical research. Thermo Fisher Scientific supplies this compound at ≥97% purity, making it suitable for applications such as antimicrobial susceptibility testing, gene regulation in Tet-inducible systems, and bacterial inhibition studies.

This high-purity form of doxycycline hyclate is provided as a white to yellow crystalline powder, with a well-defined composition including water and ethanol solvates. The product meets rigorous quality criteria, including infrared identity testing and HPLC assay ≥96%.

Key Features

  • Purity ≥97%, HPLC-verified
  • White to yellow crystalline powder
  • Supplied in glass bottles for chemical stability
  • Controlled moisture content (1.4–2.8%)
  • Stored under refrigeration for long-term stability
  • Suitable for antibiotic screening, Tet-On/Tet-Off systems, and microbial assays
  • Supplied with batch-specific Certificate of Analysis and SDS

Chemical & Physical Properties

PropertySpecification
CAS Number24390-14-5
Chemical FormulaC₂₂H₂₄N₂O₈·HCl·0.5H₂O·0.5C₂H₆O
Molecular Weight512.94 g/mol (503.94 anhydrous basis)
AppearanceWhite to yellow powder
Purity (HPLC)≥96.0%
Water Content1.4% to 2.8% (Karl Fischer titration)
Storage ConditionsRefrigerate (2–8 °C)
MDL NumberMFCD07357237
Hazard ClassificationIrritant (GHS07), Health Hazard (GHS08)

Packaging Options

Pack SizePackaging Type
5 gGlass bottle for solids
25 gGlass bottle for solids
100 gGlass bottle for solids

Applications

  • Antimicrobial research: Broad-spectrum bacterial inhibition
  • Gene regulation: Use in Tet-On/Tet-Off inducible expression systems
  • Pharmacological studies: Investigation of tetracycline derivatives
  • Bacterial susceptibility assays and MIC testing
  • Veterinary and agricultural research involving doxycycline analogs
  • In vitro studies of tetracycline-responsive transcription

Safety & Handling

  • Classified as Irritant and Health Hazard
  • Handle in a chemical fume hood with appropriate PPE (lab coat, gloves, goggles)
  • Avoid inhalation of dust and prolonged exposure
  • Store refrigerated in a tightly closed container
  • Dispose according to local and institutional chemical safety protocols
  • Refer to SDS (msds_ALFAA44606) for full hazard and handling guidance


Thermo Fisher Scientific’s Doxycycline Hyclate ≥97% provides a reliable, high-purity antibiotic for use in cell culture, microbiological testing, gene expression regulation, and related applications. Its precise formulation and consistent performance make it a valuable tool in both academic and pharmaceutical research environments requiring robust antimicrobial agents and inducible gene regulation systems.


  • Pack Size:   100g 5g 25g
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