Thermo Scientific™ ChromaCare™ LC-MS Instrument Flush Solution

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Composition
25% Acetonitrile, 25% Methanol, 25% Water, 25% 2-Propanol

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Specifications:
Application Analytical Chemistry, Mass Spectrometry
Storage Temperature Room Temperature
Product Type Laboratory Chemical Forms Liquid
Product Brand Thermo Fisher Scientific™, thermo Scientific
Product Grade Analytical grade

The Thermo Scientific™ ChromaCare™ LC-MS Instrument Flush Solution is a high-purity solvent blend specifically formulated for cleaning, conditioning, and maintaining UHPLC-MS and LC-MS analytical systems. Designed to effectively remove contaminants and residues from chromatography flow paths, this flush solution helps stabilize system baselines, improve analytical performance, and prolong instrument lifespan.

This ready-to-use solution contains a balanced mixture of polar protic and aprotic solvents, ensuring efficient removal of a wide range of contaminants without damaging sensitive instrument components. It is particularly suitable for system installation, preventative maintenance, and routine cleaning of LC-MS and UHPLC-MS systems.

Key Features

  • LC-MS grade flush solution for instrument cleaning and conditioning
  • Optimized solvent blend for effective contaminant removal
  • Helps stabilize baseline and improve analytical performance
  • Supports UHPLC-MS system installation and maintenance
  • Reduces carryover and contamination in chromatography systems
  • Supplied in high-quality borosilicate glass bottle
  • Compatible with modern UHPLC-MS and LC-MS systems

Composition

The ChromaCare™ LC-MS Instrument Flush Solution consists of a balanced solvent mixture:

ComponentConcentration
Acetonitrile25%
Methanol25%
Water25%
2-Propanol (Isopropanol, IPA)25%

This solvent combination provides excellent cleaning efficiency for removing both polar and non-polar contaminants.

Principle of Operation

The flush solution is used to clean the LC-MS system flow path, including solvent lines, pumps, injectors, columns, and detectors. Its balanced solvent composition dissolves and removes accumulated residues, contaminants, and impurities that may affect chromatographic performance.

By reducing contamination and stabilizing system baselines, the flush solution improves sensitivity, reproducibility, and analytical accuracy.

Applications

The ChromaCare™ LC-MS Instrument Flush Solution is ideal for:

  • UHPLC-MS and LC-MS system installation
  • Routine instrument cleaning and maintenance
  • Chromatography system conditioning
  • Preventative maintenance of analytical instruments
  • Baseline stabilization and performance optimization
  • Pharmaceutical, biotechnology, and analytical laboratories

Compatible with systems such as:

  • Thermo Scientific™ Vanquish™ UHPLC systems
  • Thermo Scientific™ UltiMate™ UHPLC systems
  • Triple quadrupole and high-resolution LC-MS systems

Technical Specifications

ParameterSpecification
Product NameChromaCare™ LC-MS Instrument Flush Solution
Catalog NumberT111101000
Volume1 Liter
GradeLC-MS Grade
Composition25% Acetonitrile, 25% Methanol, 25% Water, 25% 2-Propanol
Physical FormLiquid
ColorColorless
PackagingBorosilicate Glass Bottle
CAS Numbers75-05-8; 67-56-1; 67-63-0; 7732-18-5
CertificationACT Ecolabel (Silver)
ApplicationLC-MS and UHPLC-MS system cleaning and maintenance
UseResearch Use Only (RUO)

Advantages

  • Improves LC-MS instrument performance and stability
  • Removes a wide range of contaminants effectively
  • Reduces baseline noise and signal interference
  • Extends instrument lifespan
  • Ready-to-use formulation for convenient operation
  • Suitable for routine maintenance and system installation

The Thermo Scientific™ ChromaCare™ LC-MS Instrument Flush Solution is an essential reagent for maintaining optimal performance and reliability of LC-MS and UHPLC-MS systems. Its high-purity solvent blend ensures effective cleaning, improved analytical accuracy, and prolonged instrument life, making it an indispensable tool for analytical chemistry, pharmaceutical, biotechnology, and research laboratories.

  • Pack Size:   6 x 1L 1 x 1L
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