Thermo Scientific™ β-Propiolactone ≥97%

Thermo Scientific™ beta-Propiolactone (BPL) is a clear, colorless liquid with ≥97% purity, widely used as a sterilizing and sporicidal agent in research and industrial applications. It is highly effective for inactivating viruses, bacteria, and spores without damaging antigenic properties, making it ideal for vaccine production and biomedical research.

Additionally, beta-propiolactone serves as a valuable chemical intermediate in the manufacture of acrylic acid, its esters, and other synthetic compounds.

Applications

• Sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes.
• Sporicidal treatment in biomedical and laboratory settings.
• Intermediate in the synthesis of acrylic acid, acrylate esters, and other organic compounds.
• Virus inactivation for antigen preparation in vaccine development.
• Chemical research requiring reactive lactones.

Chemical & Physical Properties

Safety & Storage

• Hazards: Flammable liquid; should be handled in a fume hood with appropriate PPE.
• Storage: Store in a dedicated flammable storage cabinet away from heat, sparks, and ignition sources.
• Temperature: Ambient (room temperature), away from direct sunlight.
• Classification: RUO – For Research Use Only.

References

1. Goodman, C. H. et al. J. Virol. Methods, 2015, 223, 19–24.
2. Pawar, S. D. et al. J. Virol. Methods, 2015, 222, 28–33.

Thermo Scientific™ beta-Propiolactone, 97% is a high-quality sterilizing agent and chemical intermediate trusted in virology research, vaccine production, and organic synthesis. Its broad sterilizing spectrum, combined with miscibility in water and organic solvents, makes it a versatile reagent for biomedical and industrial applications.