Thermo Scientific™ 4-Nitrophenol 99%

4-Nitrophenol (4-NP), also known as para-nitrophenol, is a highly pure, pale-yellow crystalline compound widely used as a chemical intermediate and research reagent. With the molecular formula C₆H₅NO₃ and a molecular weight of 139.11 g/mol, 4-NP plays a critical role in both industrial synthesis and academic studies focused on environmental degradation and toxicology.

Chemical Properties:

• CAS Number: 100-02-7
• Molecular Formula: C₆H₅NO₃
• Molecular Weight: 139.11 g/mol
• Melting Point: 112–115 °C
• Boiling Point: 279 °C (760 mmHg)
• Density: 1.48 g/cm³ (20 °C)
• Flash Point: 169 °C
• Storage Temperature: Ambient
• Hazard Classification:
  • UN: 1663
  • ADR: 6.1, III (Toxic substances)
  • GHS Symbols: GHS06 (Toxic), GHS08 (Health Hazard)

Applications:

• Pharmaceutical Intermediate:
  4-NP is a precursor for 4-aminophenol (4-AP), an important building block in the synthesis of acetaminophen (paracetamol) and other analgesic and antipyretic drugs.
• Environmental & Photocatalytic Research:
  Used extensively in degradation studies involving nanomaterials (e.g., CdS nanoparticles) for environmental remediation.
• Enzyme Substrate:
  Frequently used in biochemical assays as a chromogenic substrate, due to the color change associated with its reduction or hydrolysis.

Specifications:

• Purity (GC): ≥98.5%
• Titration with NaOH: 96.0–104.0%
• Appearance: Yellow to brown crystalline powder or chunks
• Infrared Spectrum: Conforms

Available Pack Sizes:

Thermo Fisher Scientific’s 4-Nitrophenol (99%) is a high-purity reagent suitable for both pharmaceutical synthesis and environmental degradation studies. Its consistent performance in catalytic, enzymatic, and synthetic applications makes it a reliable choice for chemists, researchers, and industrial scientists. As a toxic compound, it must be handled with appropriate safety measures in place.