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Sigma-Aldrich™ Caffeine, Reference Standard, Vial of 250 mg
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Specifications:
| Application | chromatography | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Standards | Forms | Solid |
| Product Brand | Sigma-Aldrich | ||
| Product Grade | Analytical grade | Formula | C₈H₁₀N₄O₂ |
Sigma-Aldrich™ Caffeine Reference Standard is a high-purity, well-characterized xanthine alkaloid supplied for analytical, quality control, and research applications. As one of the most widely studied and regulated compounds in food, beverage, pharmaceutical, and biological research, caffeine serves as a benchmark reference material for chromatographic and spectroscopic analyses.
This reference standard is suitable for method development, system suitability testing, calibration, and validation in regulated and research laboratories.
Key Features
- Certified Sigma Reference Standard – Suitable for QC and regulatory workflows
- High Chemical Purity & Identity Assurance
- Crystalline Powder Form – Easy handling and accurate weighing
- Supplied in Amber Vial – Protects from light-induced degradation
- Widely Used Analytical Marker – Food, pharma, and biological research
- Backed by Sigma-Aldrich™ Quality – Trusted global reference standards
Chemical & Technical Information
| Parameter | Specification |
|---|---|
| Chemical Name | Caffeine |
| Synonyms | 1,3,7-Trimethylxanthine |
| CAS Number | 58-08-2 |
| Molecular Formula | C₈H₁₀N₄O₂ |
| Molecular Weight | 194.19 g/mol |
| EC Number | 200-362-1 |
| MDL Number | MFCD00005758 |
| Beilstein / Reaxys | 17705 |
| PubChem ID | 24892436 |
| SMILES | CN1C(=O)N(C)c2ncn(C)c2C1=O |
| InChI Key | RYYVLZVUVIJVGH-UHFFFAOYSA-N |
| Physical Form | Crystalline powder |
| Melting Point | 234–236.5 °C |
| Solubility | Water: 18.7 g/L at 16 °C |
| Quality Level | 200 |
Available Pack Options
| Pack Size | SKU |
|---|---|
| 1 vial (250 mg) | C1778-1VL |
| 5 vials (250 mg each) | C1778-5VL |
Applications
- Analytical reference standard for HPLC, GC, and LC-MS
- Quality control and system suitability testing
- Food & beverage caffeine analysis
- Pharmaceutical and nutraceutical research
- Biological and receptor interaction studies
Biological Relevance (Research Context)
Caffeine is a well-known adenosine receptor antagonist and phosphodiesterase inhibitor, commonly referenced in studies involving ADORA receptors and PDE enzymes, making it valuable in pharmacological and biochemical research.
Sigma-Aldrich™ Caffeine Reference Standard (250 mg) is a high-quality, reliable analytical standard ideal for quantitative analysis, method validation, and research applications across food, pharmaceutical, and biological laboratories. Its certified identity, robust documentation, and trusted Sigma-Aldrich™ quality make it an essential reference material for accurate and reproducible analytical results.
- Pack Size: 5/pk 1/pk