Sigma-Aldrich™ β-Carotene, Pharmaceutical Secondary Standard; Certified Reference Material

Sigma-Aldrich™ β-Carotene is supplied as a pharmaceutical secondary standard and Certified Reference Material (CRM) for use in quality control, analytical method validation, and pharmaceutical testing. With a molecular formula of C₄₀H₅₆ and a molecular weight of 536.87 g/mol, it is a solid, neat format carotenoid traceable to USP (United States Pharmacopeia) primary standard 1065480.

β-Carotene is the most important of the provitamins A and functions as an antioxidant. It is widely present in fruits and vegetables, also used as a food supplement and colorant. This standard is suitable for HPLC, GC, and other chromatographic techniques, enabling accurate quantification of β-carotene in pharmaceutical formulations, biological samples, and food matrices.

Key Features

• Pharmaceutical Secondary Standard – cost-effective alternative to in-house standards.
• Certified Reference Material (CRM) – multi-traceable to USP and EP primary standards.
• High reliability – quality level 300 for pharma QC and regulatory compliance.
• Versatile analytical use – suitable for HPLC and GC techniques.
• Provitamin A & antioxidant – biologically relevant carotenoid for nutrition and pharma research.
• Neat solid format – convenient for calibration and assay development.

Applications

• Pharmaceutical testing – method development, validation, and release testing.
• Food & beverage QC – analysis of β-carotene in nutritional products.
• Biological research – quantification in serum, plasma, fruits, and vegetables.
• Calibration & standards – reliable material for HPLC, GC, and multi-lab comparability.

Technical Specifications

Available Formats

Sigma-Aldrich™ β-Carotene Pharmaceutical Secondary Standard provides laboratories with a certified, traceable reference material for pharmaceutical quality control, food analysis, and chromatographic calibration. As both a CRM and USP-traceable secondary standard, it ensures accuracy, reproducibility, and regulatory compliance across multiple analytical applications.