Sigma-Aldrich Aflatoxin Mix 4 solution analytical standard

Multi-component aflatoxin standard for HPLC, UHPLC, and GC analysis

Sigma-Aldrich™ Aflatoxin Mix 4 is a high-precision, ready-to-use analytical standard designed for accurate quantification and calibration of the four naturally occurring aflatoxins: B1, B2, G1, and G2. Prepared in acetonitrile with certified concentrations, this multi-component mix provides traceability, reproducibility, and accuracy for food safety testing, mycotoxin surveillance, laboratory accreditation workflows, and regulatory compliance.

Aflatoxins are toxic secondary metabolites primarily produced by Aspergillus flavus, A. parasiticus, and A. nomius. Among the 20+ aflatoxins known, B1, B2, G1, and G2 are of greatest significance in regulatory testing due to their toxicity and prevalence in contaminated food and agricultural commodities.

Key Features

• Certified analytical standard for aflatoxins B1, B2, G1, and G2.
• Ready-to-use multi-component solution in acetonitrile.
• Ideal for HPLC, UHPLC-FLD, and GC applications.
• Supports method calibration, validation, LOD/LOQ studies, and recovery experiments.
• Ensures reliable quantification in foodstuffs, grains, coffee, nuts, spices, cosmetics, and personal care products.
• Strict manufacturing quality ensures lot-to-lot consistency.
• Frozen storage (–20 °C) for stability and extended shelf life.

Concentrations

• 0.5 µg/mL Aflatoxin B2
• 0.5 µg/mL Aflatoxin G2
• 2 µg/mL Aflatoxin B1
• 2 µg/mL Aflatoxin G1
  Solvent: Acetonitrile

Applications

Food & Agricultural Testing

Used for the quantification of aflatoxins in:

• Coffee beans and ground coffee
• Maize, rice, sorghum, and cereal meals
• Peanuts and peanut-based products
• Spices, grains, and animal feed
• Baby foods and fortified flours

Analytical Method Development

• Calibration of HPLC and UHPLC-FLD systems
• GC method optimization for aflatoxin screening
• Validation of extraction and cleanup workflows
• Linearity, detection limit, and quantification limit studies

Quality Assurance & Research

• Supports regulatory compliance:
  • EU Food Safety Standards
  • FDA Mycotoxin Limits
  • Codex Alimentarius
• Method verification for ISO/IEC 17025 accredited laboratories

Technical Specifications

Ordering Information

Sigma-Aldrich™ Aflatoxin Mix 4 Solution is a high-accuracy, ready-to-use analytical standard essential for mycotoxin quantification across food, agricultural, cosmetic, and environmental matrices. With certified concentrations of aflatoxins B1, B2, G1, and G2, it ensures accuracy in calibration, validation, and routine monitoring. Its proven reliability and compatibility with HPLC, UHPLC-FLD, and GC techniques make it an indispensable reference material for laboratories committed to food safety, quality control, and regulatory compliance.