Sigma-Aldrich 5-Sulfosalicylic acid dihydrate reagent grade, ≥99%, ReagentPlus®

High-purity reagent for analytical, coordination chemistry, and materials science applications

5-Sulfosalicylic acid dihydrate is a reagent-grade, high-purity organic acid (≥99%, ReagentPlus®) with both carboxylic acid and sulfonic acid functional groups, making it a versatile metal-chelating ligand. It is widely used in coordination chemistry, catalysis, electrochemistry, and nanoparticle synthesis due to its strong complexation ability and multifunctional reactivity.

This compound is highly soluble in water (100 mg/mL, producing a clear, colorless solution) and is stable under standard laboratory conditions. It is suitable for research, synthesis, and analytical applications that require reliable and reproducible performance.

Key Features

• High Purity – ≥99% (ReagentPlus® grade)
• Dual Functional Groups – Carboxylic and sulfonic acid moieties enable strong metal chelation
• Water-Soluble – 100 mg/mL solubility for easy handling and preparation
• Stable Solid Form – Melting point 105–110 °C
• Versatile Applications – Coordination complex formation, catalysis, nanoparticle synthesis, and advanced materials research

Chemical & Physical Properties

Applications

• Coordination Chemistry – Used as a ligand for forming metal coordination complexes
• Catalysis – Enhances catalytic efficiency in transfer hydrogenation reactions (e.g., biomass-derived furfural to furfuryl alcohol)
• Electrochemistry – Incorporated into conductive composites (e.g., polyaniline/5-sulfosalicylic acid composites) with enhanced electrochemical performance
• Nanomaterials – Controls size and dispersion in the solvothermal synthesis of Fe₃O₄ nanoclusters for magnetic applications
• Analytical Chemistry – Used for precipitation and detection of proteins in clinical analysis

Conclusion

Sigma-Aldrich 5-Sulfosalicylic acid dihydrate, ReagentPlus®, ≥99% offers high purity, excellent solubility, and multifunctional reactivity, making it ideal for advanced coordination chemistry, catalysis, materials synthesis, and analytical applications. Its dual functional groups provide strong metal-binding capacity, enabling use in a wide range of research and industrial processes.