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Invitrogen™ SARS-CoV-2 Spike Protein S1 (C.1.2) His-tag Recombinant Protein, 100 µg
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Specifications:
| Application | Protein Assays & Analysis | ||
| Storage Temperature | -20°C | ||
| Product Type | Protein Standards | Forms | lyophilized powder |
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Molecular Biology | ||
Product Information
It is recommended that the protein be aliquoted for optimal storage.
The mutations were identified in the SARS-CoV-2 varient known as C.1.2
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein). The Spike protein is the main surface antigen of the coronavirus. The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.