ROMIL-UpS™ Methanol, Ultra LC-MS

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Ultra-High Purity Solvent for Critical Analytical Applications

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Specifications:
Application chromatography
Storage Temperature Ambient
Product Type Laboratory Chemical Forms Liquid
Product Brand Romil
Product Grade Analytical grade Formula CH₃OH

ROMIL-UpS™ Methanol Ultra LC-MS is an ultra-high purity solvent specifically developed for LC-MS, UHPLC, and critical gradient HPLC applications. Manufactured under ROMIL’s stringent UpS™ (Ultra Purity Solvents) protocols, this methanol grade delivers exceptionally low UV absorbance, ultra-low residue, minimal baseline drift, and extremely low ionic and fluorescent impurities.

Its proven LC-MS suitability and outstanding chromatographic performance make it ideal for high-sensitivity, trace-level analysis, where solvent purity is essential for accurate and reproducible results.

Key Features

  • Ultra LC-MS Grade – Designed for the most demanding analytical workflows
  • Excellent UV Transparency – Suitable for low-wavelength detection
  • Ultra-Low Residue & Impurity Levels – Enhanced sensitivity and reproducibility
  • LC-MS Compatible – Passes suitability testing
  • Outstanding Gradient Performance – Minimal noise and baseline drift
  • Extremely Low Ionic & Fluorescent Contaminants

Analytical Specifications

General Purity

ParameterSpecification
Assay>99.9%
Water<0.02%
Residue after Evaporation<0.0001%
Acidity<0.0003 meq/g
Alkalinity<0.0002 meq/g

UV Transparency

WavelengthTransmission
205 nm>10%
210 nm>50%
225 nm>80%
240 nm>95%
265–400 nm>99%

Gradient & Baseline Performance

TestSpecification
Gradient Use Test (230 nm)<0.002 AU
Gradient Use Test (254 nm)<0.002 AU
Baseline Drift @ 230 nm<0.02 AU

Fluorescence Impurities (as Quinine)

WavelengthSpecification
254 nm<1 ppb
365 nm<1 ppb

Trace Ionic Impurities

ElementLimit
Ag, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn<10 ppb each
Al, Ca<25 ppb each
Na<50 ppb

LC-MS Compatibility

  • Suitability for LC-MS: Passes test

Applications

  • Liquid chromatography–mass spectrometry (LC-MS / LC-MS/MS)
  • Ultra-high-performance liquid chromatography (UHPLC)
  • Critical gradient HPLC applications
  • Trace-level impurity analysis
  • Pharmaceutical, environmental, and research laboratories

Available Pack Sizes

Pack SizeProduct Code
1 LH411M
2.5 LH411L


ROMIL-UpS™ Methanol Ultra LC-MS is a premium-grade analytical solvent engineered for laboratories that demand maximum sensitivity, consistency, and analytical confidence. With exceptional UV transparency, ultra-low impurity levels, and verified LC-MS performance, it is an ideal choice for critical gradient HPLC, UHPLC, and advanced mass spectrometry workflows.

  • Pack Size:   Glass bottle, 1L Glass bottle, 2.5L

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