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Specifications:
| Application | molecular biology | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Amino Acid & Biochemicals | Forms | Solid |
| Product Brand | MedChem Express | ||
| Product Grade | Molecular Biology | ||
Phytohemagglutinin (PHA-M) is a plant-derived lectin isolated from Phaseolus vulgaris (common bean) and widely used as a potent T-cell mitogen in immunology and cell biology research. The MCE Phytohemagglutinin 80% preparation is designed for in vitro stimulation of lymphocytes, enabling studies on immune activation, cytokine production, and cell proliferation.
PHA-M is commonly used to activate human peripheral blood mononuclear cells (PBMCs) and other immune cells, making it a valuable reagent in immunological assays, cancer research, and cellular signaling studies.
Key Features
Potent T-Cell Activator
- Stimulates T-cell proliferation and metabolic activity
- Widely used in lymphocyte transformation tests (LTT)
Immune Response Modulation
-
Induces cytokine production including:
- IL-2, IL-6, IL-1β, TNF-α, IFN-γ, IL-17
- Activates signaling pathways such as NF-κB and COX-2
Versatile Research Applications
- Suitable for PBMC stimulation and immune profiling
-
Used in studies involving:
- Cell proliferation
- Apoptosis
- Inflammatory signaling
Well-Characterized Biological Activity
- Demonstrates dose- and time-dependent cellular effects
- Alters cell morphology and induces metabolic and organelle changes
High Purity & Reliable Performance
- ≥80% purity for consistent experimental results
- Suitable for reproducible in vitro assays
Applications
- Immunology research (T-cell activation and proliferation)
- Cytokine expression and immune response studies
- Cancer and inflammation research
- Cell signaling pathway analysis
- Toxicology and apoptosis studies
Technical Specifications
| Parameter | Description |
|---|---|
| Product Name | Phytohemagglutinin (PHA-M) |
| Brand | MedChemExpress (MCE) |
| CAS Number | 9008-97-3 |
| Purity | ≥80% |
| Source | Phaseolus vulgaris (common bean) |
| Form | Solid |
| Color | White to light yellow |
| Target | T-cell activation / apoptosis pathways |
| Application | In vitro research |
| Storage | 4°C, protect from light |
| Stability (Solution) | -80°C (6 months), -20°C (1 month) |
Ordering Information
| Catalog Number | Size |
|---|---|
| HY-N7038-5MG | 5 mg |
| HY-N7038-10MG | 10 mg |
| HY-N7038-25MG | 25 mg |
| HY-N7038-50MG | 50 mg |
| HY-N7038-100MG | 100 mg |
The MCE Phytohemagglutinin (PHA-M) 80% is a powerful and widely used reagent for immune cell activation and functional studies. Its ability to stimulate T-cells and modulate cytokine expression makes it an essential tool for laboratories conducting immunology, oncology, and cellular biology research. With consistent performance and well-characterized activity, it supports reliable and reproducible experimental outcomes.
- Pack Size: 5 mg 25 mg 50 mg 100 mg 10 mg