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Specifications:
| Application | molecular biology | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Laboratory Chemical | Forms | Solid |
| Product Brand | MedChem Express | ||
| Product Grade | Analytical grade | Formula | (C₁₄H₂₅NO₂₀S₃)ₙ · xNa |
Heparin Sodium Salt, also known as Sodium Heparin or Sodium Heparinate, is a widely used anticoagulant compound that binds reversibly to Antithrombin III (ATIII) and significantly accelerates the inactivation of key coagulation enzymes, including thrombin (Factor IIa) and Factor Xa.
In addition to its classical role in coagulation studies, Heparin Sodium Salt has been shown to significantly inhibit exosome–cell interactions, making it a valuable research tool in extracellular vesicle biology, immunology, and cell signaling applications.
This product is supplied as a white to off-white solid and is intended strictly for research use.
Key Features
- Potent anticoagulant through ATIII-mediated inhibition
- Targets thrombin (Factor IIa) and Factor Xa pathways
- Reversibly binds Antithrombin III (ATIII)
- Useful in coagulation cascade and thrombosis research
- Reported inhibitor of exosome–cell interaction
- High-charge linear polysaccharide polymer structure
- Suitable for biochemical, immunological, and cell biology studies
Mechanism of Action
Heparin Sodium Salt functions primarily by enhancing the inhibitory activity of Antithrombin III against serine proteases in the coagulation cascade. Binding of heparin to ATIII increases the rate of thrombin inhibition by up to 2000-fold through formation of a ternary complex.
Heparin is also known to interact with growth factor signaling pathways, including stabilization of FGF–FGFR binding and promotion of receptor dimerization.
Product Information
| Parameter | Specification |
|---|---|
| Product Name | Heparin Sodium Salt |
| Synonyms | Sodium heparin; Sodium heparinate |
| Catalog Number | HY-17567A |
| CAS Number | 9041-08-1 |
| Target | Antithrombin III (ATIII) |
| Formula | (C₁₄H₂₅NO₂₀S₃)ₙ · xNa |
| Appearance | Solid |
| Color | White to off-white |
| Shipping Condition | Room temperature (may vary by region) |
| Storage Condition | 4°C, sealed, protected from moisture |
Available Sizes & Ordering Information
| Size | Code |
|---|---|
| 100 mg | HY-17567A-100MG |
| 500 mg | HY-17567A-500MG |
| 1 g | HY-17567A-1G |
Handling & Storage Recommendations
- Store sealed at 4°C, away from moisture
-
For prepared solutions:
- –80°C: stable up to 6 months
- –20°C: stable up to 1 month
- Avoid repeated freeze–thaw cycles
Applications
Heparin Sodium Salt is widely used in:
- Coagulation and thrombosis research
- Antithrombin III activity assays
- Thrombin and Factor Xa inhibition studies
- Exosome uptake and extracellular vesicle interaction research
- Growth factor signaling studies (FGF/FGFR pathways)
- Immunology and inflammation research
Regulatory Status
For Research Use Only. Not for use in diagnostic or therapeutic procedures. Not for sale to patients.
MCE Heparin Sodium Salt (HY-17567A) is a versatile research-grade anticoagulant compound with well-established activity through Antithrombin III-mediated inhibition of thrombin and Factor Xa. Its additional role in modulating exosome–cell interactions and growth factor signaling makes it an important reagent for coagulation biology, extracellular vesicle research, and cell signaling studies.
- Pack Size: 100mg 1g 500mg