Liofilchem™ MTS™ Clindamycin CD 0.016-256, MIC Test strips

The Liofilchem™ MTS™ Clindamycin CD 0.016-256 MIC Test Strips are advanced diagnostic tools designed for the quantitative determination of the Minimum Inhibitory Concentration (MIC) of Clindamycin, a lincosamide antibiotic. These strips provide precise, reliable results for assessing bacterial susceptibility to Clindamycin, making them essential for clinical diagnostics, antimicrobial resistance surveillance, and research.

Key Features

1. Broad MIC Range

• Covers a comprehensive concentration range from 0.016 to 256 μg/mL, allowing detection of both low- and high-level resistance.

2. Gradient Diffusion Technology

• Predefined antibiotic gradient on each strip ensures precise MIC determination.
• Facilitates accurate and reproducible results without the need for complex broth dilution methods.

3. High Sensitivity and Specificity

• Detects susceptibility and resistance in Gram-positive bacteria, including:
  • Staphylococcus aureus (including MRSA).
  • Streptococcus spp.
  • Anaerobic pathogens like Clostridium spp.

4. Standardized Testing

• Fully compliant with global standards such as EUCAST, CLSI, and ISO, ensuring consistency across laboratories.

5. Simple and User-Friendly

• Easy to apply on agar plates with clear visual MIC interpretation.
• MIC is determined where the inhibition ellipse intersects the strip’s gradient scale.

6. Rapid Turnaround Time

• Provides actionable results within 16–24 hours, expediting therapeutic decisions.

7. Long Shelf Life

• Durable and stable when stored under recommended conditions (-20°C).

Applications

1. Clinical Diagnostics

• Assess the effectiveness of Clindamycin in treating infections caused by:
  • Staphylococcus spp.
  • Streptococcus spp.
  • Anaerobic bacteria associated with skin, soft tissue, and respiratory infections.

2. Detection of Inducible Resistance

• Conduct the D-test alongside erythromycin to detect inducible clindamycin resistance in Staphylococcus aureus and Streptococcus spp.

3. Surveillance of Antibiotic Resistance

• Monitor trends in Clindamycin resistance among Gram-positive pathogens in healthcare settings.

4. Research and Development

• Investigate the efficacy of Clindamycin in experimental studies and evaluate resistance mechanisms.

How It Works

1. Sample Preparation:
   • Prepare a bacterial suspension standardized to 0.5 McFarland.
2. Application:
   • Spread the suspension evenly on an agar plate and place the MTS strip on the surface.
3. Incubation:
   • Incubate the plate at 35–37°C for 16–24 hours.
4. Result Interpretation:
   • Read the MIC value where the ellipse of inhibition intersects the strip’s scale.

Specifications

Advantages

1. Precision

• Accurate and reliable MIC values for critical clinical and research needs.

2. Efficiency

• Faster results compared to traditional broth dilution methods.

3. Versatility

• Suitable for routine testing and advanced research applications.

4. Ease of Use

• Streamlined workflow integrates easily into standard laboratory practices.

Limitations

• May require additional confirmatory tests (e.g., molecular diagnostics) for detailed resistance profiling.
• Not suitable for fastidious organisms without protocol adjustments.

Why Choose Liofilchem™ MTS™ Clindamycin CD?

• Accuracy: Provides precise and reproducible MIC results for a wide range of pathogens.
• Speed: Delivers actionable results within a single day, aiding in timely therapeutic decisions.
• Compliance: Meets international standards for consistent and reliable performance.

The Liofilchem™ MTS™ Clindamycin CD MIC Test Strips are an essential tool for clinical microbiology labs, enabling efficient antibiotic susceptibility testing and resistance detection.