Liofilchem® ESC Swabs with Letheen Broth

Liofilchem® ESC Swabs with Letheen Broth are ready-to-use environmental sampling devices designed for the microbiological monitoring of surfaces exposed to disinfectants, sanitizers, and preservative-containing products.

Each ESC swab is pre-filled with Letheen Broth, a neutralizing medium specifically formulated to inactivate residual antimicrobial agents—particularly quaternary ammonium compounds—allowing accurate recovery and detection of microorganisms from treated surfaces.

These swabs are widely used in pharmaceutical cleanrooms, cosmetic manufacturing, food processing environments, and healthcare hygiene monitoring, where reliable microbial recovery is essential for quality control and regulatory compliance.

Key Features and Benefits

Neutralization of Disinfectant Residues

Letheen Broth contains neutralizing components such as lecithin and surfactants, enabling effective neutralization of:

• Quaternary ammonium disinfectants
• Preservatives in cosmetic products
• Residual sanitizers on surfaces
• Cleaning agent carryover that may inhibit microbial growth

This ensures that microbial detection reflects true contamination levels rather than false-negative results caused by disinfectant interference.

Ready-to-Use Environmental Sampling Format

ESC Swabs provide a convenient, standardized sampling solution:

• Pre-moistened swab system
• No preparation required
• Ideal for routine hygiene audits
• Suitable for surface monitoring programs

Multiple Volume Options for Flexible Applications

Available in three Letheen Broth fill volumes:

• 1 mL – compact sampling, controlled moisture
• 5 mL – general-purpose environmental monitoring
• 10 mL – high-moisture sampling for larger or dry surfaces

Reliable Microbial Recovery

Designed to support the recovery of bacteria commonly monitored in controlled environments, including:

• Staphylococcus aureus
• Escherichia coli
• Salmonella spp.
• Pseudomonas aeruginosa
• General aerobic mesophilic flora

Professional Quality for Regulated Industries

ESC Swabs are widely applied in:

• GMP microbiology laboratories
• Pharmaceutical manufacturing QC
• Cosmetics microbiological testing (ISO-based workflows)
• Food and beverage hygiene monitoring
• Surface bioburden assessment

Applications

Liofilchem® ESC Swabs – Letheen Broth are recommended for:

Environmental Monitoring

• Cleanroom surface sampling
• Equipment hygiene verification
• Production area microbial surveillance

Disinfectant Effectiveness Testing

• Monitoring surfaces after sanitization
• Validation of cleaning protocols
• Neutralization of antimicrobial carryover

Cosmetic and Personal Care Microbiology

• Microbial enumeration in preservative-treated environments
• Support for ISO 21149 cosmetic microbiology workflows

Food & Beverage Safety

• Hygiene monitoring of food-contact surfaces
• Routine sanitation verification programs

Product Specifications

Ordering Information

Unique Advantages

• Neutralizes disinfectant residues for accurate microbial recovery
• Supports GMP-compliant hygiene monitoring programs
• Available in multiple broth volumes for different surface conditions
• Trusted Liofilchem® quality for regulated microbiology laboratories
• Ideal for pharmaceutical, cosmetic, food, and healthcare applications

Liofilchem® ESC Swabs with Letheen Broth provide a reliable, ready-to-use solution for surface sampling and environmental microbiological monitoring, especially in settings where disinfectant residues could inhibit microbial growth.

They are an essential tool for ensuring cleanliness verification, contamination control, and compliance with hygiene standards across pharmaceutical, cosmetic, and food production industries.