Invitrogen™ PureLink™ Pro 96 Genomic DNA Purification Kit, 4 x 96 Preps

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    Specifications:
    Application DNA Extraction and Purification
    Storage Temperature Room Temperature, 2-8°C
    Product Type Sample Prep Forms Kit with Various components
    Product Brand Thermo Fisher Scientific™, Invitrogen
    Product Grade Molecular Biology

    The Invitrogen™ PureLink™ Pro 96 Genomic DNA Purification Kit provides a high-throughput solution for isolating high-yield, high-purity genomic DNA (gDNA) from a wide range of sample types. Designed for use in a 96-well silica plate format, this kit enables parallel processing of up to 96 samples in ~45 minutes, ensuring efficiency and reproducibility for large-scale projects.

    With its optimized buffers and advanced plate design, the kit delivers A260/A280 and A260/A230 absorbance ratios of ~1.8, indicating DNA free from protein, RNA, guanidine, or other contaminants. The semi-skirted plate with annular collar nozzles prevents cross-contamination and improves drying, minimizing ethanol carryover—crucial for downstream success.

    Key Features

    • Flexible Sample Compatibility – One kit supports gDNA isolation from blood, tissue, cells, FFPE, saliva, buccal swabs, blood spots, bacterial and yeast cells, and tail biopsies.
    • High Quality Output – Consistently high-purity gDNA with clean absorbance ratios.
    • High Throughput – 96-well plate format enables manual or automated processing.
    • Improved Design – Semi-skirted plates compatible with centrifugation, benchtop vacuums, and robotic liquid handling systems.
    • Fast Workflow – DNA ready for use in ~45 minutes, including homogenization.

    Applications

    • PCR amplification and qPCR.
    • DNA sequencing and NGS library preparation.
    • Southern blotting and nucleic acid hybridization.
    • Cloning and molecular biology research.
    • Long-term genomic studies using high-purity gDNA.

    Technical Specifications

    ParameterDetails
    Product TypeGenomic DNA Purification Kit (96-well)
    Catalog NumberK182104A (4 × 96 preps)
    Isolation TechnologySilica plate
    Sample TypesBlood, tissues, cells, FFPE, saliva, buccal swabs, blood spots, bacteria, yeast, mouse/rat tails
    Sample Input≤25 mg tissue, ≤200 µL blood, ≤10⁹ bacterial cells, ≤10⁷ yeast cells
    YieldUp to 0.5 mg gDNA (binding capacity)
    DNA QualityA260/A280 and A260/A230 ~1.8
    Elution Volume50–200 µL
    Test Time~45 minutes (including homogenization)
    Format96-well plate
    Prep ScaleMini-prep scale per well
    High-ThroughputCompatible with centrifuge, vacuum manifold, and robotic automation
    Shipping ConditionRoom temperature
    StorageBuffers at RT; Proteinase K at 4 °C for long-term storage
    Unit SizeEach kit (4 × 96 preps)

    Kit Contents

    • PureLink Pro 96 Genomic Lysis/Binding Buffer
    • Digestion Buffer
    • Wash Buffers 1 & 2
    • Elution Buffer
    • RNase A
    • Proteinase K
    • Genomic DNA Filter Plates
    • 96 Deep Well Blocks
    • Foil Tape

    Unique Advantages

    • One kit for multiple sample sources, reducing the need for specialized kits.
    • Optimized buffer system ensures reproducibility across diverse inputs.
    • Suitable for both manual labs and automated robotic workflows.
    • Outperforms competitor kits in both DNA yield and purity.


    The Invitrogen™ PureLink™ Pro 96 Genomic DNA Purification Kit is a robust, high-throughput solution for extracting high-quality gDNA from diverse biological sources. Delivering fast, consistent, and ultraclean DNA, this kit is ideal for laboratories conducting large-scale genomic studies, sequencing projects, or molecular biology workflows requiring reliable gDNA.

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