Eppendorf™ Combitips™ advanced tips for Multipette™ multi-dispensers

Eppendorf™ Combitips™ Advanced are precision dispenser tips designed for use with Eppendorf Repeater® and Multipette® multi-dispensers. These high-quality dispenser tips ensure accurate, reliable, and efficient liquid handling across a wide range of laboratory applications. Thanks to their advanced design and features, Combitips™ Advanced offer unmatched performance, particularly for handling challenging liquids that might be difficult to manage with conventional pipetting tips.

Key Features and Benefits

• Positive Displacement Pipetting: Combitips™ Advanced utilize positive displacement pipetting, a principle that ensures the exact volume of liquid is dispensed, regardless of the liquid's physical properties. This design overcomes the challenges posed by liquids with varying viscosity, volatility, density, and temperature, ensuring accurate dispensing every time. This is crucial when working with non-aqueous solutions or liquids that are hard to handle using traditional pipetting methods.
• Versatile Volume Range: Eppendorf Combitips™ Advanced are available in 9 different volume sizes, ranging from 0.1 mL to 50 mL, which makes them suitable for a variety of dispensing volumes. With the ability to dispense increments as small as 100 nanoliters, these tips provide excellent versatility and precision for various lab applications, whether it's for micro- or macro-volume dispensing.
• Elongated Design for Easy Access: The elongated Combitips™ Advanced in 2.5 mL, 5.0 mL, and 10 mL volumes are designed to reach the bottom of most common laboratory vessels, making them ideal for large sample containers and enabling efficient sample handling.
• Wide Range of Purity Grades: Combitips™ Advanced are offered in five different purity grades to accommodate various laboratory needs:
  • Eppendorf Quality
  • PCR Clean
  • Forensic DNA Grade
  • Sterile
  • Biopur®
  This range ensures that users can choose the best tip based on the level of purity required for their specific applications, from basic laboratory experiments to high-precision work like DNA sequencing or PCR-based workflows.
• Sustainability: Eppendorf Combitips™ Advanced are ACT® labeled by My Green Lab®, a non-profit organization that certifies products based on their environmental impact. This makes Combitips™ Advanced an excellent choice for laboratories aiming to adopt more sustainable lab practices without compromising on quality or performance.
• Hermetically Sealed Piston: The integrated piston in Combitips™ Advanced ensures that the system is hermetically sealed, which prevents contamination by aerosols when handling radioactive, toxic, or volatile liquids. This makes the tips suitable for safe handling of hazardous materials, offering enhanced protection for both the user and the environment.

Applications

Eppendorf Combitips™ Advanced are highly versatile and are used in a wide range of laboratory tasks, including:

1. High-Precision Dispensing:
   Combitips™ Advanced are ideal for precise liquid handling in both routine and specialized laboratory tasks, including DNA extraction, buffer preparation, and sample dilution.
2. Multi-Tube Pipetting:
   The Multipette® and Repeater® systems work seamlessly with Combitips™ Advanced to allow for rapid multi-tube dispensing and accurate serial dilutions, making these tips essential for high-throughput applications.
3. PCR and DNA Workflows:
   The PCR Clean, Forensic DNA Grade, and Biopur® Combitips™ Advanced are specifically designed for sensitive molecular biology applications, ensuring that contamination-free dispensing of reagents and samples is achieved.
4. Large-Volume Dispensing:
   The larger Combitips™ Advanced in the 2.5 mL, 5.0 mL, and 10 mL volumes are particularly useful for large-volume liquid handling, such as in the preparation of media, reagents, and buffer solutions in cell culture or chemical research.

Historical and Innovative Design

Eppendorf pioneered the Repeater®/Combitips® system in 1978, introducing the first-ever multi-dispensing pipette system. The system allows for filling the tip once and dispensing multiple times, streamlining laboratory workflows. This revolutionary concept continues to be a key component of modern laboratories, particularly for plate-based assays or experiments involving serial sample handling.

Certifications

• ACT® Environmental Impact Factor:
  The ACT® label, awarded by My Green Lab®, helps users make informed choices regarding sustainability, ensuring that Combitips™ Advanced meet the growing demand for environmentally conscious products in modern laboratories.
• Lot-Specific Quality Certificates:
  Combitips™ Advanced come with general quality certificates. For those requiring extra assurances, tips are available in PCR Clean, Forensic DNA Grade, Sterile, or Biopur® grades, with lot-specific certificates for each purity grade.

Important Notes

• Compatibility:
  Combitips™ Advanced are designed exclusively for use with Eppendorf Repeater® and Multipette® multi-dispensers. These tips should not be used with other pipette brands, ensuring optimal performance and accuracy.
• Caution for Alcohol-Sensitive Surfaces:
  Combitips™ Advanced tips may not be suitable for use with alcohol-sensitive surfaces like acrylic or fiberglass. Always test on a small area to ensure compatibility.

Eppendorf Combitips™ Advanced provide a highly accurate, versatile, and environmentally responsible solution for a wide range of laboratory liquid handling applications. Whether you are performing high-throughput dispensing, molecular biology workflows, or chemical sample preparation, these tips are designed to meet the high standards required for precision and sustainability in modern laboratories. With their innovative design, robust performance, and commitment to sustainable lab practices, Combitips™ Advanced remain a staple in laboratories around the world.