Atom Sci. Congo Red C.I. 22120

Anionic Benzidine-Based Diazo Dye for Amyloid Staining and Cell Wall Studies

Congo Red is a classic histochemical stain widely used in biological and pathological research. As an anionic diazo dye, it binds specifically to amyloid structures, β-D-glucans, and other polysaccharides, making it a valuable tool in the study of protein aggregation, fungal cell walls, and plant cell microstructures. Its sharp colorimetric transition and strong binding properties support its use in microscopy, histology, and amyloid detection assays.

Key Features

• High purity C.I. 22120 dye for biological and analytical applications
• Binds to amyloid fibrils and β-glucans with high affinity
• Distinct pH-dependent color shift (blue to red from pH 3.5–5.0)
• λmax at 585 nm suitable for spectrophotometric quantification
• Stable dry powder form with <2.5% moisture content

Specifications

Applications

• Amyloid Detection – Histochemical stain for visualizing amyloid deposits in brain and tissue sections
• Fungal Cell Wall Studies – Used to inhibit and study fungal growth (e.g., Cryptococcus neoformans)
• Plant Histology – Confocal microscopy staining of plant cell walls (e.g., potato tissue analysis)
• Biophysical Research – Investigation of β-D-glucans, galactoglucomannans, and polysaccharide interactions
• Protein Aggregation – Quantification of amyloid β-peptide aggregation and fibrillization

Ordering Information

Congo Red (C.I. 22120) is a reliable and widely used dye for staining amyloid structures, studying fungal cell walls, and visualizing polysaccharide networks in plant and biological tissues. Its strong binding properties and well-characterized optical behavior make it indispensable in both research and clinical histology laboratories.