Apollo Scientific™ Amoxicillin Trihydrate, cell culture tested

Amoxicillin trihydrate is a broad-spectrum, semi-synthetic β-lactam antibiotic belonging to the penicillin class. Supplied by Apollo Scientific, this research-grade compound is widely used in microbiology, molecular biology, and cell culture applications to study bacterial growth inhibition and antibiotic susceptibility.

Amoxicillin exerts its antibacterial activity by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), ultimately leading to cell lysis. As a β-lactam antibiotic, it is sensitive to β-lactamase enzymes, making it particularly useful in resistance mechanism studies and in combination research with β-lactamase inhibitors.

Mechanism of Action

Amoxicillin interferes with the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. By preventing cross-linking of peptidoglycan chains, it compromises cell wall integrity, resulting in osmotic instability and bacterial cell death. This mechanism makes amoxicillin effective against a wide range of Gram-positive and selected Gram-negative bacteria, while also serving as a benchmark compound in antimicrobial research.

Key Features & Advantages

• Broad-spectrum β-lactam antibiotic for research applications
• Inhibitor of bacterial cell wall synthesis
• Sensitive to β-lactamase, enabling resistance pathway studies
• Cell culture tested for compatibility with in vitro systems
• High chemical purity and consistency
• Suitable for microbiology, antibiotic resistance, and molecular biology research

Applications

• Antibacterial activity and susceptibility studies
• Antibiotic resistance and β-lactamase research
• Microbial growth inhibition assays
• Cell culture contamination control studies
• Reference compound in antimicrobial method development
• Educational and academic laboratory research

Chemical Information

Synonyms include:

• 6-[2-Amino-2-(4-hydroxyphenyl)-acetyl]amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
• (2S,5R,6R)-6-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
• (2S,5R,6S)-6-((S)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
• Amoxicillin Trihydrate

Physical Properties

• Appearance: Solid
• Hydration State: Trihydrate
• Solubility: Water soluble (typical for penicillin-class antibiotics)

Packaging & Ordering Information

Storage & Stability

• Store refrigerated at 2–8 °C
• Protect from moisture and light
• Follow recommended storage to maintain stability and activity

Quality & Documentation

• Supplied by Apollo Scientific
• Accompanied by Certificates of Analysis (CoA)
• Lot traceability available
• Manufactured under controlled quality systems

Apollo Scientific™ Amoxicillin Trihydrate is a reliable, cell culture–tested β-lactam antibiotic widely used in microbiological and molecular biology research. Its well-characterized mechanism of action, sensitivity to β-lactamase, and consistent quality make it an essential reference compound for studies involving bacterial cell wall synthesis, antimicrobial resistance, and in vitro bacterial control. Available in multiple pack sizes, it provides flexibility and confidence for both routine laboratory use and advanced research applications.