Specifications:
| Application | cell Signalling | ||
| Storage Temperature | Ambient | ||
| Product Type | Antifungals | Forms | Powder |
| Product Brand | Apollo Scientific | ||
| Product Grade | Molecular Biology | Formula | C₃H₄N₂ |
Imidazole is a heteroaromatic organic compound with a five-membered ring structure containing two nitrogen atoms. It is a white to off-white crystalline solid with a wide range of applications in biochemistry, molecular biology, pharmaceuticals, and catalysis. Imidazole is widely used in protein purification workflows, particularly in Ni-NTA affinity chromatography for the elution of His-tagged proteins.
Key Features
- High purity Imidazole (≥99%).
- Available in 500 g, 1 kg, and 2.5 kg bottles.
- Essential for Ni-NTA protein purification (His-tag elution).
- Used in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals.
- Functions as a buffering agent in biochemical applications.
Specifications
| Parameter | Details |
|---|---|
| Product Name | Imidazole |
| CAS Number | 288-32-4 |
| Molecular Formula | C₃H₄N₂ |
| Molecular Weight | 68.08 g/mol |
| MDL Number | MFCD00005183 |
| EINECS Number | 206-019-2 |
| Purity | ≥99% |
| Appearance | White to off-white crystalline solid |
| Melting Point | 85–91 °C |
| Boiling Point | 235 °C |
| Flash Point | 145 °C |
| Storage Temperature | Ambient |
| UN Number | 3263 |
| ADR Classification | Class 8 (Corrosive), Packing Group II |
| Hazard Statements | Corrosive (H314), Irritant, Health hazard |
| Packaging Options | 500 g (OR5102-500G), 1 kg (OR5102-1KG), 2.5 kg (R5102-2.5KG) |
Applications
- Protein purification: Imidazole competes with histidine residues to release His-tagged proteins in affinity chromatography.
- Biochemical research: Used as a buffering agent in enzymatic assays.
- Pharmaceutical synthesis: A building block for antifungals, antivirals, and other therapeutic agents.
- Catalysis and materials science: Ligand for transition metal complexes and ionic liquids.
- Agriculture: Precursor in the production of agrochemicals.
Safety Information
- Classified as Corrosive and Irritant.
- May cause skin burns, eye damage, and respiratory irritation.
- Handle with gloves, goggles, and protective clothing.
- Store in tightly sealed containers at ambient temperature.
- UN 3263, ADR Class 8, Packing Group II.
Imidazole (CAS 288-32-4) is a versatile heteroaromatic compound used in biochemistry, pharmaceuticals, catalysis, and industrial chemistry. Its critical role in His-tagged protein purification makes it indispensable in molecular biology and biotechnology research. With high purity, multiple pack sizes, and broad applications, this reagent is a reliable choice for academic, industrial, and pharmaceutical laboratories.
- Pack Size: 1kg 500g 2.5kg
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