Apollo Sci. Chloramphenicol ≥99%

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Specifications:
Application Microbiology
Storage Temperature 2-8°C
Product Type Antibiotic Forms Powder
Product Brand Apollo Scientific
Product Grade Microbiology grade Formula Cl₂CHCONHCH(CH₂OH)CH(OH)C₆H₄NO₂

Chloramphenicol is a broad-spectrum bacteriostatic antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits activity against both Gram-positive and Gram-negative bacteria and is widely used in microbiological and molecular biology applications. Due to its high purity (≥99%), this product is ideal for sensitive laboratory applications, including cell culture testing.

Product Features:

  1. High Purity:
    • With a purity of ≥99%, the product ensures consistent and reliable results in experimental settings.
    • Free from contaminants, making it suitable for precision research.
  2. Broad-Spectrum Antibiotic:
    • Effective against a wide range of bacteria, including Gram-positive and Gram-negative species.
    • Used for studying resistance mechanisms and for microbial selection in laboratory settings.
  3. Cell Culture Tested:
    • Proven compatibility with cell cultures, ensuring minimal cytotoxicity for non-target organisms.
  4. Chemical Stability:
    • Molecular Formula: Cl₂CHCONHCH(CH₂OH)CH(OH)C₆H₄NO₂
    • Molecular Weight: 323.13 g/mol
    • Melting Point: 148–152°C, indicating a stable crystalline structure.
  5. Storage:
    • Recommended storage at refrigerator temperature (2–8°C) to maintain efficacy and prevent degradation.

Applications:

  1. Antibiotic Selection in Microbiology:
    • Commonly used for selection of chloramphenicol-resistant bacteria in cloning experiments.
    • Effective in preventing bacterial contamination in cell culture media.
  2. Molecular Biology:
    • Integrated into research workflows to maintain selective pressure on genetically modified organisms carrying chloramphenicol resistance genes.
  3. Microbial Research:
    • Used in the study of bacterial resistance mechanisms and antibiotic efficacy testing.
  4. Cell Culture Maintenance:
    • Prevents contamination during long-term culture of sensitive cell lines.
  5. Protein Synthesis Inhibition Studies:
    • Used as a tool to investigate mechanisms of bacterial protein synthesis.

Specifications:

PropertyDetails
SynonymsChloromycetin®, Tega-Cetin, (R,R)-Chloramphenicol
PotencyBacteriostatic activity
Molecular FormulaCl₂CHCONHCH(CH₂OH)CH(OH)C₆H₄NO₂
Molecular Weight323.13 g/mol
Melting Point148–152°C
Purity≥99%
Storage TemperatureRefrigerator (2–8°C)
MDL NumberMFCD00078159
CAS Number56-75-7
EINECS200-287-4

Safety Notes:

  • Toxicity: Handle with care as chloramphenicol is associated with bone marrow suppression in humans at certain exposure levels.
  • Personal Protective Equipment (PPE): Use gloves, lab coat, and eye protection while handling.
  • Disposal: Follow proper laboratory waste disposal guidelines and local regulations for antibiotic disposal.

Key Benefits:

  • High purity ensures reproducibility in scientific experiments.
  • Effective across a broad range of bacteria, making it a versatile choice for microbiological and molecular applications.
  • Cell culture tested, ensuring reliability in contamination prevention.

Apollo Sci. Chloramphenicol ≥99% powder is a dependable choice for researchers and laboratories requiring a high-quality antibiotic for microbial selection, resistance studies, and contamination control.

  • Pack Size:   500 Grams 250 Grams 100 Grams
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