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Specifications:
| Application | Cell culture, Microbiology | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Antibiotic | Forms | Powder |
| Product Brand | Apollo Scientific | ||
| Product Grade | Cell Culture | Formula | C₆₆H₁₀₃N₁₇O₁₆S₁ |
Bacitracin is a cyclic polypeptide antibiotic primarily active against Gram-positive bacteria. It is isolated from Bacillus subtilis and related species and acts by interfering with bacterial cell wall biosynthesis, specifically by inhibiting the dephosphorylation of bactoprenol pyrophosphate—a critical step in peptidoglycan transport. This mechanism makes bacitracin a valuable reagent in both antimicrobial susceptibility testing (AST) and selective culture media preparation.
Due to its strong activity against Streptococcus pyogenes and Staphylococcus aureus, bacitracin is widely used in clinical bacteriology laboratories, particularly in differentiating Group A streptococci from other β-hemolytic streptococci through the bacitracin sensitivity test.
Bacitracin from Apollo Scientific is supplied as a thermally stable, research-grade powder and is ideal for use in media formulation, antibiotic resistance profiling, and phenotypic identification protocols. It is free from thermophilic contaminants, ensuring compatibility with sensitive microbiological and pharmaceutical applications.
Applications
- Antimicrobial Susceptibility Testing (AST): Used in the disc diffusion method to assess bacitracin sensitivity of bacterial isolates.
- Microbial Identification: Key component in presumptive identification of Group A Streptococcus pyogenes.
- Selective Culture Media: Incorporated into selective and differential media to inhibit the growth of non-target organisms.
- Pharmaceutical Quality Control: Employed in microbiological assay systems for evaluating antibacterial potency.
- Academic and Industrial Research: Useful in antibiotic mechanism studies and resistance gene expression assays.
Available Pack Sizes
| Catalog Number | Pack Type | Pack Size |
|---|---|---|
| BIB0106-5G | Bottle | 5 g |
| BIB0106-25G | Bottle | 25 g |
Safety & Handling
- Classification: Irritant – handle in accordance with institutional chemical safety procedures
- Personal Protective Equipment (PPE): Use gloves, lab coat, and eye protection
- Storage Conditions: Store refrigerated between 2°C and 8°C
- Stability: Stable under recommended storage conditions; avoid excessive humidity or heat
- Disposal: Dispose of in accordance with local environmental safety regulations
Apollo Scientific’s Bacitracin is a high-quality, research-grade antimicrobial agent that plays a critical role in microbiological diagnostics, selective culture media development, and antibiotic resistance profiling. With excellent purity, thermal stability, and compliance with research standards, this product is trusted in both clinical and industrial microbiology laboratories. Its precision formulation supports reliable and reproducible results across a wide range of microbiological applications.
- Pack Size: 5g 25g