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Gibco™ LV-MAX™ Lentiviral Production System
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Specifications:
| Application | Cell culture, Bioprocessing | ||
| Storage Temperature | 2-8°C, Store Cells in Liquid Nitrogen untill ready to use | ||
| Product Type | Molecular Biology Reagent | Forms | Liquid |
| Product Brand | Thermo Fisher Scientific™, Gibco | ||
| Product Grade | Cell Culture | ||
The Gibco™ LV-MAX™ Lentiviral Production System is the first optimized, scalable, and high-yield lentiviral vector production platform. It is designed to facilitate large-scale transient lentivirus production in suspension-adapted HEK 293-derived Viral Production Cells under chemically defined, serum-free, and protein-free conditions.
This system integrates LV-MAX Production Medium, LV-MAX Transfection Reagents, and LV-MAX Enhancer and Supplement, offering a superior alternative to conventional polyethylenimine (PEI)-based transfection methods.
Key Features & Benefits
1. High-Titer Lentiviral Production
- Achieves greater than 1 × 10⁸ TU/mL (unconcentrated lentiviral vectors - LVVs-GFP).
- Optimized enhancer and supplement maximize virus functionality and infectivity.
2. Scalable Suspension System
- Adapted for suspension HEK 293-derived cells, enabling seamless scaling.
- Compatible with 96-deep well plates up to 2-L bioreactors for flexible production.
3. Serum-Free, Chemically Defined System
- No animal-origin components, reducing batch variability and regulatory concerns.
- Protein-free formulation minimizes the risk of immune response in downstream applications.
4. Optimized for Transient Lentivirus Production
- Efficient lipid nanoparticle-based transfection reagent enhances vector yield and transduction efficiency.
- Simplified workflow integrates into current transient production processes.
System Components & Storage
| Component | Quantity | Storage Conditions |
|---|---|---|
| LV-MAX Production Medium | 1 L | 2–8°C, protect from light |
| LV-MAX Transfection Kit | 0.3 L | 2–8°C, protect from light |
| Viral Production Cells | 2 vials | Store in liquid nitrogen (Do not store at -80°C) |
Additional Required Reagent (Not Included)
- Gibco™ Opti-MEM™ I Reduced Serum Medium (Cat. No. 31985062).
Specifications
| Property | Details |
|---|---|
| Delivery Type | Lentiviral, Transfection |
| Cell Line | Viral Production Cell-Line |
| Culture Type | Suspension Cell Culture |
| Expression System | Transient |
| Formulation | Liquid |
| Product Type | Lentiviral Production System |
| Product Line | LV-MAX™ |
| Quantity | 1 Kit |
| Shipping Conditions | Room Temperature, Wet or Dry Ice |
| Unit Size | Each |
Applications
1. Lentiviral Vector Production for Gene Therapy & Research
- Ideal for high-yield lentivirus generation for gene delivery applications.
- Supports scalable transient production of lentiviral vectors in biotech and academic research.
2. Cell & Gene Therapy Development
- Enables large-scale production of lentiviral vectors for CAR-T cell engineering.
- Enhanced viral titers improve gene transfer efficiency.
3. Bioprocessing & Virus-Based Drug Discovery
- Designed for reliable, reproducible lentivirus generation in suspension culture systems.
- Optimized for industrial-scale viral vector production.
Storage & Handling
- Store LV-MAX Production Medium and Transfection Kit at 2–8°C and protect from light.
- Store Viral Production Cells in liquid nitrogen until ready to use (do not store at -80°C).
- Maintain aseptic conditions during handling to prevent contamination.
Ordering Information
| Catalog Number | Description | Quantity |
|---|---|---|
| A35684 | Gibco™ LV-MAX™ Lentiviral Production System | 1 Kit |
The Gibco™ LV-MAX™ Lentiviral Production System is a scalable, high-yield lentiviral vector production platform that integrates a suspension-adapted HEK 293-derived cell line, optimized transfection reagents, and serum-free medium. Offering greater than 1 × 10⁸ TU/mL, this system is ideal for gene therapy research, cell engineering, and virus-based drug development.