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Thermo Scientific™ Pierce™ Protease Inhibitor Tablets
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Specifications:
| Application | molecular biology, Protein Purification | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Molecular Biology Reagent | Forms | Tablets |
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Molecular Biology | ||
Thermo Scientific™ Pierce™ Protease Inhibitor Tablets are a convenient, ready-to-use solution designed to protect proteins from proteolytic degradation during cell lysis and protein extraction. These tablets contain a broad-spectrum formulation of protease inhibitors that effectively inhibit multiple classes of proteases commonly released during sample preparation.
Optimized for laboratory efficiency, each tablet dissolves rapidly to form a clear solution and is sufficient for preparing 50 mL of lysis buffer or sample solution, ensuring reliable and reproducible protein preservation across a wide range of applications.
Key Features
Broad-Spectrum Protease Protection
- Inhibits serine, cysteine, aspartic proteases, and aminopeptidases
- Prevents degradation of target proteins during extraction
- Maintains protein integrity for downstream analysis
Convenient Tablet Format
- Pre-measured tablets eliminate preparation errors
- Rapid dissolution into clear solution
- One tablet sufficient for 50 mL of buffer or lysate
Optimized for Laboratory Workflows
- Compatible with detergent-based lysis buffers
- Suitable for use with Pierce BCA Protein Assay
- Easily integrated into standard protein extraction protocols
Cost-Effective and Reliable
- Economical alternative to liquid inhibitor cocktails
- Consistent batch-to-batch performance
- Long shelf life under recommended storage conditions
Applications
- Protein extraction from tissues and cultured cells
- Cell lysis workflows
- Proteomics and protein characterization studies
- Western blotting and immunoassays
- Enzyme and protein stability studies
Mechanism of Action
During cell lysis, proteases are released and can rapidly degrade proteins of interest. Pierce Protease Inhibitor Tablets contain a combination of inhibitors that target different protease classes:
- AEBSF – serine protease inhibitor
- Aprotinin – serine protease inhibitor
- Bestatin – aminopeptidase inhibitor
- E-64 – cysteine protease inhibitor
- Leupeptin – serine and cysteine protease inhibitor
- Pepstatin A – aspartic protease inhibitor
This multi-target inhibition ensures comprehensive protection of proteins during sample preparation.
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Type | Protease Inhibitor |
| Format | Tablets (solid) |
| Quantity | 20 Tablets |
| Inhibitor Type | Broad-spectrum protease inhibitors |
| Sufficient For | 50 mL per tablet |
| Compatibility | Detergent-based lysis buffers, BCA assay |
| Shipping Condition | Room temperature |
| Storage | 2°C to 8°C |
| Product Line | Pierce™ |
| Unit Size | Each |
Usage Instructions
- Dissolve 1 tablet in 50 mL of buffer or lysate
- Mix until fully dissolved before use
- Add to lysis buffer prior to protein extraction
Product Information
| Catalog Number | Description | Quantity |
|---|---|---|
| A32963 | Pierce Protease Inhibitor Tablets | 20 Tablets |
Storage and Stability
- Store at 2°C to 8°C
- Stable for up to 12 months under recommended conditions
- Keep tightly sealed to prevent moisture exposure
Related Products
- Thermo Scientific Pierce Protease Inhibitor Tablets EDTA-free
- Pierce Protease Inhibitor Mini Tablets
- Pierce Phosphatase Inhibitor Mini Tablets
- Pierce Protease and Phosphatase Inhibitor Mini Tablets
Thermo Scientific™ Pierce™ Protease Inhibitor Tablets provide a reliable, easy-to-use solution for protecting proteins during extraction and analysis. With broad-spectrum inhibition, excellent compatibility, and a convenient tablet format, they are an essential reagent for laboratories engaged in protein research and proteomics workflows.