Liofilchem® Mecillinam MEC, Antimicrobial Susceptibility Discs, 10 µg

The Liofilchem® Mecillinam (MEC) Antimicrobial Susceptibility Discs (10 µg) are high-quality, standardized discs designed for in vitro antimicrobial susceptibility testing (AST) of bacterial isolates. These discs are used in Kirby-Bauer disk diffusion testing, providing accurate and reproducible results in clinical microbiology laboratories, hospitals, and pharmaceutical research settings.

Mecillinam is a β-lactam antibiotic belonging to the penicillin class, primarily effective against Gram-negative bacteria, particularly Enterobacteriaceae. It is commonly used for urinary tract infection (UTI) treatment studies and multi-drug resistance (MDR) bacterial testing.

Key Features & Benefits

1. Reliable & Standardized Antimicrobial Susceptibility Testing

• Preloaded 10 µg Mecillinam discs for accurate zone inhibition measurement.
• Designed for use in Kirby-Bauer disk diffusion method.
• Ensures reliable and reproducible results in clinical and research microbiology laboratories.

2. Effective Against Gram-Negative Bacteria

• Highly active against Enterobacteriaceae, including:
  • Escherichia coli (E. coli)
  • Klebsiella spp.
  • Proteus spp.
  • Salmonella spp.
  • Shigella spp.
• Used in resistance profiling for β-lactamase-producing bacteria.

3. Compliance with International Standards

• Manufactured according to CLSI (Clinical & Laboratory Standards Institute) and EUCAST (European Committee on Antimicrobial Susceptibility Testing) guidelines.
• Sterile, ready-to-use discs for immediate application.
• Ensures quality control and standardization for laboratory AST procedures.

4. Convenient & Easy-to-Use Packaging

• Individually packaged for contamination-free handling.
• Long shelf-life and stable storage conditions.
• Ideal for use in manual and automated disc dispensers.

Specifications

Use Cases

1. Clinical Microbiology & Hospital Laboratories

• Determination of bacterial susceptibility to Mecillinam in patient-derived isolates.
• Used in hospitals for routine AST in urinary tract infections (UTIs) caused by E. coli and Klebsiella spp.
• Guides antibiotic therapy selection in multidrug-resistant (MDR) infections.

2. Pharmaceutical & Antibiotic Development

• Research on novel β-lactamase inhibitors and their effects on Mecillinam resistance.
• Screening bacterial isolates for susceptibility in pharmaceutical R&D.
• Evaluation of drug-resistant Enterobacteriaceae in pharmaceutical testing.

3. Epidemiological & Public Health Surveillance

• Tracking and monitoring antibiotic resistance trends globally.
• Surveillance of Mecillinam-resistant bacterial strains in community and hospital-acquired infections.
• Supporting antimicrobial stewardship programs in healthcare institutions.

4. Veterinary Microbiology & Food Safety

• Detection of antibiotic resistance in animal bacterial isolates.
• Foodborne pathogen screening for antimicrobial susceptibility testing.
• Use in research on zoonotic infections and bacterial transmission from animals to humans.

Storage & Handling

• Store at 2°C – 8°C to maintain potency.
• Use sterile forceps or an automatic disc dispenser for application.
• Avoid moisture and direct sunlight exposure to prevent degradation.

Ordering Information

The Liofilchem® Mecillinam (MEC) Antimicrobial Susceptibility Discs (10 µg) are essential for reliable AST in clinical, research, and epidemiological settings. These sterile, ready-to-use discs comply with CLSI and EUCAST standards, making them ideal for hospital labs, pharmaceutical research, and global antimicrobial resistance monitoring.