Liofilchem® Roxithromycin RXT Antimicrobial Susceptibility Discs, 15 µg

Standardized Disc Diffusion Reagent for In Vitro Antibiotic Susceptibility Testing

Liofilchem® Roxithromycin RXT Antimicrobial Susceptibility Discs are precision-prepared paper discs impregnated with 15 µg of Roxithromycin, a macrolide antibiotic used in the treatment of respiratory tract, skin, and soft tissue infections. These discs are designed for in vitro antimicrobial susceptibility testing (AST) by the Kirby-Bauer disc diffusion method, enabling laboratories to determine the susceptibility profile of clinical bacterial isolates to roxithromycin.

Each disc is manufactured under strict quality control in compliance with EUCAST and CLSI guidelines, ensuring consistent potency and diffusion characteristics. The discs are individually packaged in blister packs to maintain stability, sterility, and ease of use in routine microbiological testing.

Key Features & Benefits

• Standardized Dose – Contains 15 µg of Roxithromycin per disc for reliable and reproducible testing
• High-Quality Manufacturing – Produced under ISO 9001 and ISO 13485 certifications for clinical diagnostics
• Blister Packaged – Maintains disc integrity and sterility until point of use
• EUCAST/CLSI Compliant – Suitable for globally recognized AST protocols
• Optimized for Diffusion – Ensures accurate zone diameter measurement and interpretation

Use Cases & Applications

1. Clinical Microbiology Laboratories

Used for routine susceptibility testing of respiratory pathogens, such as Streptococcus pneumoniae and Haemophilus influenzae, or skin and soft tissue pathogens like Staphylococcus aureus:

• Support decision-making for empirical or targeted antibiotic therapy
• Detect resistance mechanisms including macrolide resistance (MLS_B phenotype)
• Contribute to local antimicrobial surveillance programs

2. Hospital and Reference Laboratories

• Monitor antibiotic resistance trends in macrolide treatment regimens
• Validate resistance phenotypes in surveillance of Streptococcus pyogenes and atypical respiratory pathogens
• Support infection control and antimicrobial stewardship efforts

3. Veterinary and Research Laboratories

• Evaluate the efficacy of roxithromycin in non-human bacterial isolates from animals
• Study resistance development in bacteria under macrolide pressure
• Conduct pharmaceutical and academic research on macrolide pharmacodynamics

Technical Specifications

Liofilchem® Roxithromycin RXT 15 µg Discs are a reliable, high-quality tool for performing standardized antimicrobial susceptibility testing of bacterial isolates. Whether used in clinical microbiology, antimicrobial surveillance, veterinary diagnostics, or resistance research, these discs provide precise zone measurements essential for effective antibiotic stewardship and resistance monitoring.