Thermo Scientific™ Vanquish™ LightPipe™ Flow Cell, 10mm, for the Vanquish™ Diode Array Detector HL

The Thermo Scientific™ Vanquish™ LightPipe™ Flow Cell (6083.0100B) is a precision-engineered optical flow cell designed exclusively for the Vanquish™ Diode Array Detector HL (DAD HL). Featuring Thermo Scientific’s advanced LightPipe™ technology, this flow cell delivers unmatched signal-to-noise performance, exceptional baseline stability, and superior detection sensitivity across UHPLC applications.

The LightPipe™ design maximizes optical efficiency through an extended light path length, ultra-low baseline noise, and minimized peak dispersion—resulting in highly accurate quantitation and reliable impurity profiling, even at trace levels. Reduced refractive index and thermal effects ensure stable, drift-free baselines, enabling robust method performance during long sequences, fast gradients, and UHPLC workflows.

Key Features & Benefits

1. Exceptional Signal-to-Noise Performance

• Long optical light path for increased sensitivity
• Ultra-low noise floor ensures reliable trace analysis
• Ideal for detecting impurities, low-level analytes, and narrow UHPLC peaks

2. Low Dispersion for High-Resolution UHPLC

• 2 μL illuminated volume
• 0.8 μL dispersion volume
• Minimizes band broadening for sharp, symmetrical UHPLC peaks
• Optimized for fast-gradient and high-efficiency separations

3. Stable Baseline for Accurate Peak Integration

• Reduced refractive index (RI) effects
• Minimized thermal influence across temperature changes
• Produces flat, drift-free chromatographic baselines

4. Robust Pressure Handling

• Maximum pressure rating: 6 MPa (60 bar / 870 psi)
• Compatible with UHPLC flow rates and long sequences
• Supports rugged routine and advanced analytical workflows

5. Designed for the DAD HL Detector

• Fully integrated with Vanquish™ Diode Array Detector HL
• Ensures maximum spectral accuracy across the full DAD HL wavelength range (190–680 nm)
• High optical throughput for superior sensitivity

Applications

• UHPLC impurity profiling
• Trace-level detection of pharmaceuticals & metabolites
• Environmental contaminant screening
• Food & beverage analysis
• Spectral peak purity determination
• Fast UHPLC separations

Specifications

The Thermo Scientific™ Vanquish™ LightPipe™ Flow Cell (10 mm) is a low-dispersion, ultra-sensitive flow cell designed for the Vanquish DAD HL, providing unmatched signal-to-noise performance, minimal baseline drift, and superior detection accuracy for UHPLC applications.