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Thermo Scientific™ Formic Acid, LC-MS Grade, 10 x 1 mL
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Specifications:
| Application | Analytical Chemistry, Mass Spectrometry | ||
| Storage Temperature | Room Temperature | ||
| Product Type | Laboratory Chemical | Forms | Tablets |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Analytical grade | Formula | HCOOH (CH₂O₂) |
Thermo Scientific™ Formic Acid, LC-MS Grade is an ultra-high purity solvent specifically designed for use in liquid chromatography–mass spectrometry (LC-MS) and high-performance liquid chromatography (HPLC) applications. Supplied in convenient, contamination-free sealed ampules, this reagent ensures optimal chromatographic performance and maximum analytical sensitivity when preparing mobile phases for protein, peptide, and biomolecule analysis.
Its exceptional purity and low contaminant levels make it ideal for sensitive LC-MS workflows, improving peak shape, enhancing ionization efficiency, and ensuring reliable analytical results.
Key Features
- LC-MS grade purity for high-sensitivity analytical applications
- Ideal for preparation of mobile phases in LC-MS and HPLC
- Improves chromatographic peak shape and separation efficiency
- Enhances ionization efficiency for mass spectrometry detection
- Supplied in sealed ampules to minimize contamination
- High purity (>99%) ensures reproducible analytical performance
- Compatible with protein, peptide, and biomolecule analysis
Principle of Use
Formic acid is commonly used as an additive in reverse-phase LC-MS mobile phases, where it provides protons to enhance ionization efficiency during mass spectrometry analysis. Its volatile nature makes it especially suitable for MS detection, as it does not suppress ionization like certain ion-pairing agents.
The addition of formic acid improves:
- Chromatographic peak shape
- Signal sensitivity
- Separation efficiency
- Mass spectrometry signal quality
Applications
Thermo Scientific LC-MS Grade Formic Acid is suitable for:
- LC-MS analysis of proteins and peptides
- HPLC and UHPLC mobile phase preparation
- Proteomics and biomolecule analysis
- Pharmaceutical and biotechnology research
- Analytical chemistry laboratories
- Environmental and food testing laboratories
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | Formic Acid, LC-MS Grade |
| Catalog Number | 28905 |
| Brand | Thermo Scientific™ Pierce™ |
| Quantity | 10 × 1 mL |
| Purity | > 99% |
| Molecular Formula | HCOOH (CH₂O₂) |
| Molecular Weight | 46.02 g/mol |
| Density | 1.22 g/mL |
| CAS Number | 64-18-6 |
| Refractive Index | 1.3701–1.3721 (20°C) |
| Flash Point | 69°C |
| Physical State | Clear liquid |
| Application | LC-MS, HPLC, UHPLC |
| Reagent Type | High-purity solvent |
| Storage Conditions | Store in cool, dry, well-ventilated area |
| Use | Research Use Only (RUO) |
Advantages
- High purity ensures accurate and reproducible results
- Improves chromatographic performance and MS sensitivity
- Convenient ampule format minimizes contamination risk
- Ideal for sensitive proteomics and analytical workflows
- Compatible with modern LC-MS and UHPLC systems
Thermo Scientific™ Formic Acid, LC-MS Grade provides the purity, reliability, and performance required for demanding LC-MS and chromatography applications. Its high-quality formulation enhances chromatographic separation and mass spectrometry sensitivity, making it an essential reagent for analytical chemistry, proteomics, pharmaceutical research, and advanced laboratory workflows.