MALDI Biotyper® RUO Matrix HCCA-portioned, 2.5mg per tube

The Bruker MALDI Biotyper® RUO Matrix HCCA-portioned is a high-purity α-cyano-4-hydroxycinnamic acid (HCCA) matrix designed for use in MALDI-TOF mass spectrometry microbial identification systems, specifically the MALDI Biotyper. Each tube contains 2.5 mg of pre-portioned HCCA for convenience and accuracy in preparation. This matrix is part of Bruker’s standardized reagents and kits that enable precise microbial identification.

• Key Features:
  1. High Purity: Ensures minimal background noise in mass spectrometry, yielding cleaner spectra.
  2. Pre-Portioned: Precisely measured for consistent results, minimizing preparation errors.
• 1. Convenience: Each pack contains 10 tubes, reducing the risk of contamination during frequent use.
  2. Optimized for MALDI-TOF MS: Formulated specifically for use with the Bruker MALDI Biotyper systems.

Applications

1. Clinical Microbiology:
   • Identification of bacteria, yeast, and other pathogens directly from cultured samples.
   • Supports rapid and accurate diagnosis, aiding antimicrobial stewardship by informing targeted therapy.
2. Pharmaceutical Quality Control:
   • Detection of microbial contamination in production environments or products.
   • Ensures compliance with Good Manufacturing Practices (GMP).
3. Food and Beverage Microbiology:
   • Identifies spoilage organisms and pathogens in raw materials, finished goods, and production lines.
   • Enhances food safety and regulatory compliance.
4. Environmental Microbiology:
   • Analyzing water or soil samples for the presence of microbial communities.
   • Useful in monitoring bioremediation processes or environmental health.
5. Veterinary Diagnostics:
   • Pathogen identification for veterinary infections, assisting in treatment decisions for animals.
6. Academic and Industrial Research:
   • Characterization of microbial strains for research or biotechnological applications.
   • Discovery of novel microbial taxa through high-resolution mass spectrometry.

Use Cases

1. Rapid Pathogen Identification in Hospitals:
   • Using the matrix with MALDI-TOF MS, laboratories can quickly identify infectious agents like Escherichia coli, Staphylococcus aureus, or Candida albicans, reducing diagnostic turnaround time.
2. Outbreak Investigations:
   • Enables fast identification of bacterial species during disease outbreaks, ensuring appropriate control measures.
3. Antibiotic Resistance Studies:
   • Identifying resistant organisms by integrating microbial identification with antimicrobial susceptibility data.
4. Quality Assurance in Biopharmaceuticals:
   • Detection and profiling of biopharmaceutical contaminants or production strains.
5. Validation of MALDI Systems:
   • Routine calibration and quality control of MALDI-TOF MS instruments to maintain analytical accuracy.

Storage and Handling

• Store at controlled room temperature as specified by Bruker’s guidelines.
• Handle in clean conditions to prevent contamination of the matrix or working area.

Product Specifications

• Matrix: α-Cyano-4-Hydroxycinnamic Acid (HCCA).
• Concentration per Tube: 2.5 mg.
• Packaging: 10 tubes per pack.
• Intended Use: For in vitro diagnostic applications, certified for MALDI-TOF MS systems.

This product is a crucial reagent in MALDI-TOF-based workflows, offering precision and reliability for various microbial identification and diagnostic applications.