Gibco™ Carbenicillin Disodium Salt, 5g

Gibco™ Carbenicillin Disodium Salt is a semi-synthetic penicillin antibiotic containing a carboxyl and benzyl group, with a mechanism of action similar to ampicillin. It inhibits bacterial cell wall synthesis, displaying selective activity against Gram-negative bacteria, while demonstrating low toxicity to plant tissues.

Compared to ampicillin, carbenicillin is more resistant to β-lactamase degradation, offering improved stability in culture systems. It is widely used in plant transformation workflows, particularly for the elimination of Agrobacterium tumefaciens following co-cultivation, and in E. coli selection assays. Carbenicillin is supplied as a sterile powder, ready to be reconstituted into stock solutions of 50–100 mg/mL in water.

Key Features

• Semi-synthetic penicillin – stable analog of ampicillin with improved β-lactamase resistance.
• Selective activity – effective against Gram-negative bacteria such as Agrobacterium and E. coli.
• Low phytotoxicity – suitable for plant tissue culture applications.
• Enhanced stability – reduces the formation of satellite colonies in long-term incubations.
• Flexible preparation – supplied as a powder; recommended stock 50–100 mg/mL.

Applications

• Plant biotechnology – elimination of Agrobacterium tumefaciens in transformation workflows.
• Bacterial selection – maintenance of plasmid vectors in E. coli cultures.
• Microbial genetics – selection for ampicillin/carbenicillin resistance markers.
• Molecular cloning – prevention of satellite colony formation in long incubations.

Technical Specifications

Available Format

Gibco™ Carbenicillin Disodium Salt provides a stable, selective, and low-toxicity antibiotic solution for plant transformation and bacterial selection. Its enhanced resistance to β-lactamase degradation ensures reproducibility and reduces satellite colony formation, making it an essential antibiotic for molecular cloning and plant biotechnology research.