VWR® Ethyl Acetate ≥99.5%, Analar Normapur® Acs, Reag. Ph. Eur. Analytical Reagent

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Specifications:
Application Analytical Chemistry
Storage Temperature Ambient
Product Type Laboratory Chemical Forms Liquid
Product Brand VWR
Product Grade Analytical grade Formula CH₃COOC₂H₅

The VWR® Ethyl Acetate ≥99.5%, Analar Normapur® ACS, Reag. Ph. Eur. is a high-purity analytical reagent-grade solvent, meeting the stringent standards of:

  • ACS (American Chemical Society) standards
  • Reag. Ph. Eur. (European Pharmacopoeia) specifications
  • Analar Normapur® quality criteria

This analytical-grade ethyl acetate is widely used in chemical analysis, chromatography, extraction processes, and synthesis applications, making it an essential reagent in pharmaceutical, industrial, and research laboratories.

Key Properties & Specifications

PropertyDetails
Chemical FormulaC₄H₈O₂
Molecular Weight88.11 g/mol
Purity≥99.5%
CAS Number141-78-6
Boiling Point76-78°C
Density0.902 g/mL at 20°C
SolubilitySlightly soluble in water, miscible with most organic solvents
GradeAnalytical Reagent (ACS, Reag. Ph. Eur., Analar Normapur®)
AppearanceClear, colorless liquid with a fruity odor
Storage ConditionsStore in a tightly sealed container at a well-ventilated place away from heat sources

Applications & Use Cases

1. Chromatography & Analytical Testing

Primary Use:

  • Solvent in High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC)
  • Used as a mobile phase in Thin Layer Chromatography (TLC)
  • Suitable for sample preparation and purification techniques

Practical Example:

A pharmaceutical quality control lab uses VWR® Ethyl Acetate in HPLC analysis to test for impurities and degradation products in drug formulations. Due to its high purity, it ensures accurate, interference-free results in analytical separations.

2. Pharmaceutical & Chemical Synthesis

Primary Use:

  • Serves as a reaction solvent for esterification and organic synthesis
  • Used in extraction and purification of active pharmaceutical ingredients (APIs)
  • Essential for solvent-mediated crystallization of pharmaceutical compounds

Practical Example:

A research laboratory in medicinal chemistry uses ethyl acetate to extract and purify synthetic drug intermediates. Its ability to selectively dissolve organic compounds while leaving behind unwanted byproducts makes it ideal for purification processes.

3. Sample Preparation & Liquid-Liquid Extraction (LLE)

Primary Use:

  • Used in extraction of organic compounds from aqueous solutions
  • Applied in toxicology and forensic science for isolating drugs, pesticides, and metabolites
  • Preferred solvent for preparing extracts for mass spectrometry (MS) analysis

Practical Example:

A forensic toxicology lab uses VWR® Ethyl Acetate for liquid-liquid extraction (LLE) of drug residues from biological samples before analysis via Gas Chromatography-Mass Spectrometry (GC-MS). Its low polarity allows for efficient separation of hydrophobic substances from aqueous matrices.

4. Industrial Applications & Quality Control

Primary Use:

  • Solvent in coatings, adhesives, and printing inks manufacturing
  • Used in flavor and fragrance production
  • Key solvent in paint and varnish removers

Practical Example:

A cosmetic manufacturer uses ethyl acetate in fragrance formulation, as it helps dissolve aromatic compounds while evaporating quickly, leaving behind only the desired scent.

5. Histology & Tissue Processing in Life Sciences

Primary Use:

  • Used in histological staining protocols
  • Facilitates tissue dehydration in slide preparation
  • Acts as a solvent for fat extraction in food analysis

Practical Example:

A pathology lab incorporates ethyl acetate in tissue processing to dehydrate samples before embedding them in paraffin, ensuring clear, high-resolution microscopic examination of cell structures.

Advantages of VWR® Ethyl Acetate ≥99.5%, Analar Normapur®

High Purity & Low Contaminants – Ensures accurate and reliable analytical results

Versatile Solvent – Suitable for chromatography, synthesis, extraction, and histology

Meets Stringent Standards – Complies with ACS, Reag. Ph. Eur., and Analar Normapur® quality requirements

Low Water Content – Prevents interference in sensitive chemical and analytical reactions

Fast Evaporation Rate – Ideal for quick-drying applications in coatings, adhesives, and fragrance industries

Storage & Safety Considerations

🔹 Storage Recommendations:

  • Keep container tightly closed in a cool, well-ventilated area.
  • Store away from heat sources, open flames, and strong oxidizing agents.

🔹 Safety Precautions:

  • Highly flammable liquid and vapor – Keep away from ignition sources.
  • Use in a fume hood to prevent inhalation of vapors.
  • Wear protective gloves and goggles when handling.

🔹 Disposal Guidelines:

  • Dispose of in accordance with local environmental regulations.
  • Do not discharge into drains, water sources, or soil.

The VWR® Ethyl Acetate ≥99.5%, Analar Normapur® ACS, Reag. Ph. Eur. is a high-purity solvent trusted for analytical, pharmaceutical, industrial, and life science applications. With its versatility, reliability, and compliance with global purity standards, it remains an essential reagent for laboratories requiring precision, efficiency, and safety in their chemical processes.

Specification Test Results

Assay (on anhydrous substance)Min. 99.5 %
IR SpectrumPasses test
Organic impuritiesPasses test
AcidityMax. 0.0006 meq/g
Boiling point76.0 - 77.5 °C
ColourationMax. 10 APHA
Density (20/4)0.899 - 0.901
Density (20/20)0.901 - 0.904
Substances coloured by H2SO4Max. 60 APHA
E/EMax. 0.1 %
Evaporation residueMax. 10 ppm
MethanolMax. 0.1 %
Methyl acetateMax. 0.1 %
iso-Propyl acetateMax. 0.06 %
n-Propyl acetateMax. 0.5 %
WaterMax. 0.03 %
Al (Aluminium)Max. 0.1 ppm
B (Boron)Max. 0.02 ppm
Ba (Barium)Max. 0.02 ppm
Ca (Calcium)Max. 0.5 ppm
Cd (Cadmium)Max. 0.05 ppm
Co (Cobalt)Max. 0.02 ppm
Cr (Chromium)Max. 0.02 ppm
Cu (Copper)Max. 0.02 ppm
Fe (Iron)Max. 0.1 ppm
K (Potassium)Max. 0.1 ppm
Mg (Magnesium)Max. 0.05 ppm
Mn (Manganese)Max. 0.02 ppm
Na (Sodium)Max. 0.5 ppm
Ni (Nickel)Max. 0.02 ppm
Pb (Lead)Max. 0.05 ppm
Sn (Tin)Max. 0.1 ppm
Sr (Strontium)Max. 0.02 ppm
Zn (Zinc)Max. 0.1 ppm
Conforms to ACSPasses test
Conforms to Reag. Ph.Eur.Passes test
  • Pack Size:   Glass bottle, 1L Plastic bottle, 1L Glass bottle, 2.5L Plastic bottle, 2.5L Plastic bottle, 5L Metal Drum, 25L 200 L
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