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VWR Acetonitrile ≥99.95%, HiPerSolv CHROMANORM® ULTRA for LC-MS, suitable for UPLC/UHPLC-MS instruments
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Specifications:
| Application | HPLC, Mass Spectrometry | ||
| Storage Temperature | Ambient | ||
| Product Type | Laboratory Chemical | Forms | Liquid |
| Product Brand | VWR | ||
| Product Grade | Analytical grade | ||
HiPerSolv CHROMANORM® ULTRA Acetonitrile is a premium-grade solvent designed for LC-MS, UPLC, and UHPLC-MS applications requiring the highest purity and spectral clarity. Filtered through a 0.2 µm filter and packaged under nitrogen to minimize contamination and oxidation, it provides exceptionally low background noise, excellent UV transparency, and ultra-low levels of trace metals and residues.
With an assay specification of ≥99.95% purity and rigorous testing for fluorescence, gradient baseline drift, and MS sensitivity (ESI+/ESI−/APCI), this solvent is optimized for high-sensitivity proteomics, metabolomics, pharmaceutical, and environmental analysis.
Key Features
- High Purity: ≥99.95% on anhydrous basis.
- Exceptional Optical Properties: Transmittance ≥98–99% between 200–230 nm.
- Ultra-Low Residues: ≤1 ppm evaporation residue, ≤100 ppm water.
- Minimal Background: Gradient ≤1 mAU at 210 nm and 254 nm.
- MS Tested: ≤2 ppb (ESI+ Reserpine), ≤20 ppb (ESI− & APCI− 4-Nitrophenol).
- Trace Metals Controlled: ≤20 ppb for Al, Ba, Ca, Cd, Co, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, Zn.
- Packaging: Inert glass bottles, nitrogen sealed, filtered at 0.2 µm.
- Safety Classification: Flammable, Irritant (UN 1648; ADR 3, II).
Specifications (Selected Highlights)
| Property | Value |
|---|---|
| Appearance | Clear, colorless liquid |
| Purity (GC) | ≥99.95% |
| Density (20 °C) | 0.786 g/cm³ |
| Boiling Point | 81.6 °C |
| Melting Point | –45.7 °C |
| Flash Point | 2 °C (closed cup) |
| UV Transparency | T200 nm ≥98%, T210 nm ≥98%, T215–230 nm ≥99% |
| Water Content (KF) | ≤100 ppm |
| Residue after Evaporation | ≤1 ppm |
| Fluorescence (Quinine) | ≤1 ppb (254/450 nm), ≤0.5 ppb (365 nm) |
| Storage Temperature | Ambient |
Applications
- LC-MS & UHPLC-MS: High-purity acetonitrile for ultra-sensitive mass spectrometry workflows.
- Proteomics & Metabolomics: Ideal for trace-level detection in complex biological samples.
- Pharmaceutical Analysis: Supports drug discovery, impurity profiling, and QA/QC.
- Environmental Testing: Suitable for pesticide, contaminant, and pollutant analysis.
- Chromatography: Exceptional baseline stability for gradient elution methods.
The HiPerSolv CHROMANORM® ULTRA Acetonitrile (≥99.95%) is engineered to deliver superior performance in LC-MS and UHPLC workflows, ensuring low background, minimal drift, and ultra-low contamination. With rigorous control of optical, chemical, and metallic impurities, it enables researchers to achieve high-sensitivity and reproducibility in proteomics, metabolomics, clinical, and pharmaceutical applications. A reliable choice for laboratories demanding the highest-grade solvents for advanced analytical workflows.
- Pack Size: Glass bottle, 1L Glass bottle, 2.5L