Thermo Scientific™ Piperidine 99%, extra pure

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Specifications:
Application Analytical Chemistry
Storage Temperature Ambient
Product Type Laboratory Chemical Forms Liquid
Product Brand Thermo Fisher Scientific™
Product Grade Analytical grade Formula C₅H₁₁N

Thermo Scientific™ Piperidine, 99%, Extra Pure is a high-quality, aliphatic heterocyclic amine widely used in organic synthesis. Known for its strong basicity and nucleophilicity, piperidine plays a key role in the formation of heterocycles, peptide synthesis, and as a base in deprotection reactions. This reagent-grade chemical conforms to rigorous purity standards (≥98.5% by GC), ensuring consistent performance in research and industrial applications.

Key Features and Benefits

  • High Purity: ≥98.5% by gas chromatography for reliable and reproducible results
  • Clarity: Supplied as a clear liquid with color ≤50 APHA
  • Certified Quality: Infrared spectrum conforms to specification
  • Low Water Content: ≤0.5% (Karl Fischer), enhancing stability for moisture-sensitive applications
  • Versatile Solvent and Base: Ideal for nucleophilic substitution and base-catalyzed transformations

Typical Applications

  • Intermediate in pharmaceutical synthesis
  • Precursor in the production of agrochemicals and rubber accelerators
  • Deprotection agent in peptide chemistry (e.g., Fmoc removal)
  • Solvent/base in cross-coupling and condensation reactions
  • Component in catalyst or ligand preparation

Technical Specifications

ParameterValue
AppearanceClear liquid
Color Scale (APHA)≤50
Purity (GC)≥98.5%
Water Content (K.F.)≤0.5%
Refractive Index (20°C)1.4510 – 1.4540
Storage ConditionsStore in a cool, well-ventilated area away from oxidizers

Packaging Options

Catalog NumberVolumePackaging
1471800101 LGlass bottle
147185000500 mLGlass bottle
1471800252.5 LGlass bottle
14718010010 LPlastic container

Safety Information

  • Hazards: Flammable liquid and vapor; causes skin and eye irritation; toxic if swallowed or inhaled
  • Handling: Use with adequate ventilation, and store away from heat or ignition sources
  • Regulatory Compliance: For Research Use Only (RUO); not for use in diagnostic or therapeutic procedures


Thermo Scientific™ Piperidine, 99%, Extra Pure is a trusted choice for demanding organic chemistry applications. With its excellent purity, reliable consistency, and broad applicability across pharmaceuticals, agrochemicals, and material sciences, this reagent is an essential component in any modern synthesis laboratory.


  • Pack Size:   100 mL 500 mL 1 LIter
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