Sigma-Aldrich Preparative TLC plates, 20 cm × 20 cm

Sigma-Aldrich Preparative TLC (Thin Layer Chromatography) plates are high-quality chromatography tools designed to separate and analyze complex mixtures. These plates provide optimal resolution and durability, making them ideal for preparative applications where larger sample loads and higher purity are required.

Key Features:

1. Dimensions and Design:
   • Size: 20 cm × 20 cm, a standard dimension suitable for preparative applications.
   • Layer Thickness Options: Available in 500 μm, 1,000 μm, and 2,000 μm to accommodate varying preparative requirements.
2. Material Composition:
   • Support Material: Durable glass support ensures structural stability and precision.
   • Matrix: Silica gel 60, which provides excellent separation efficiency and reproducibility.
3. Fluorescent Indicator:
   • Incorporated fluorescent indicator enhances visualization of separated components under UV light, making it easier to track the progress of separation.
4. Pore and Particle Size:
   • Pore Size: Medium pore diameter of 60 Å supports effective separation of a wide range of compounds.
   • Particle Size: 20–40 μm particles ensure high resolution and reproducibility.
5. Binder:
   • Organic polymer binder offers robust adhesion of the silica gel layer to the glass plate, minimizing flaking or chipping during application.
6. Packaging:
   • Supplied in a package of 25 plates, ensuring adequate stock for repetitive analyses.
7. Compatibility:
   • Suitable for preparative applications and compatible with various solvent systems.

Specifications:

Applications:

1. Preparative Chromatography:
   • Ideal for isolating and purifying compounds from complex mixtures, particularly in pharmaceutical, chemical, and natural product research.
2. Compound Analysis:
   • Used in separating and identifying organic compounds, including small molecules, peptides, and lipids.
3. Quality Control and R&D:
   • Essential in quality control to assess the purity of products and in research to isolate intermediates or target compounds.
4. Sample Visualization:
   • Equipped with a fluorescent indicator, enabling efficient UV detection of separated components.
5. Pharmaceutical and Biochemical Research:
   • Effective in drug discovery and formulation studies for compound separation and preparative purposes.
6. Food and Beverage Testing:
   • Used in the analysis of additives, contaminants, or natural compounds in food products.

Advantages:

• High Resolution: Provides sharp and distinct separations for effective compound isolation.
• Durable and Reliable: Glass support and organic polymer binder ensure mechanical strength and prevent silica layer detachment.
• Versatile: Works with a variety of solvent systems and compatible with different detection methods.
• Cost-Effective: Comes in a pack of 25 plates, providing value for laboratories with high sample throughput.

Packaging Information:

• Pack Size: 25 plates per box.
• Dimensions: 20 cm × 20 cm.
• Layer Thickness Options: 500 μm, 1,000 μm, or 2,000 μm depending on the application.

Sigma-Aldrich Preparative TLC plates are indispensable for researchers and quality control professionals seeking precise and reproducible preparative chromatographic results in a variety of industries, including pharmaceuticals, biochemistry, and environmental sciences.