Liofilchem™ MTS™ Voriconazole VO 0.002-32, MIC Test strips

The Liofilchem™ MTS™ Voriconazole MIC Test Strips are quantitative gradient diffusion assays for determining the minimum inhibitory concentration (MIC) of voriconazole (VO) against clinically relevant fungi. Each strip contains a continuous antifungal concentration gradient covering 0.002–32 µg/mL, enabling accurate determination of susceptibility across both susceptible and resistant isolates.

These strips offer a reliable agar-based alternative to reference broth microdilution methods (CLSI/EUCAST), delivering reproducible and standardized results.

Key Features

• Antifungal gradient strip for Voriconazole (VO).
• MIC range: 0.002–32 µg/mL.
• Accurate and reproducible MIC determination.
• Agar-based method, simpler than broth microdilution.
• Compatible with Candida, Aspergillus, and other pathogenic fungi.
• Adheres to CLSI/EUCAST susceptibility testing guidelines.
• Available in 10, 30, or 100 strip packs.

Use Cases

1. Clinical Microbiology Laboratories
   • Susceptibility testing of Candida spp., Aspergillus spp., and other opportunistic fungi.
   • Supports patient management in invasive fungal infections.
2. Antifungal Stewardship Programs
   • Detects voriconazole resistance, especially in azole-resistant Aspergillus fumigatus and non-albicans Candida species.
   • Guides optimized antifungal therapy to reduce resistance risk.
3. Epidemiological & Resistance Surveillance
   • Monitoring azole resistance trends in fungal pathogens.
   • Provides standardized MIC data for national and international resistance databases.
4. Research & Development
   • Comparative antifungal studies with other azoles (fluconazole, itraconazole, posaconazole).
   • Benchmarking voriconazole activity in antifungal drug discovery.

Clinical Significance

• Voriconazole is a broad-spectrum triazole antifungal widely used for invasive aspergillosis, candidemia, and serious fungal infections in immunocompromised patients.
• Resistance to voriconazole has emerged globally, particularly among Candida glabrata and azole-resistant Aspergillus fumigatus.
• MIC testing with Liofilchem™ MTS™ strips is essential to:
  • Identify resistant isolates and guide therapeutic adjustments.
  • Improve treatment outcomes in high-risk patients (e.g., transplant recipients, oncology patients).
  • Support public health by tracking resistance patterns.

Ordering Information

The Liofilchem™ MTS™ Voriconazole (VO) 0.002–32 MIC Test Strips provide a robust, standardized, and easy-to-use method for antifungal susceptibility testing. With their broad MIC range, high reproducibility, and clinical relevance, these strips are indispensable tools for clinical microbiology labs, antifungal stewardship programs, epidemiological surveillance, and research. By supporting early detection of voriconazole resistance, they play a crucial role in improving treatment outcomes and combating antifungal resistance worldwide.