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The Thermo Scientific™ Vanquish™ Flex UHPLC System is a state-of-the-art, biocompatible ultra-high performance liquid chromatography (UHPLC) platform engineered to deliver exceptional flexibility, high precision, and robust analytical performance. Designed for method development, high-throughput workflows, and complex applications, the Vanquish Flex system incorporates advanced quaternary or binary solvent blending capabilities, industry-leading pumping technology, precision sample handling, and comprehensive detection options.
Built upon the Vanquish platform’s core values—uptime, reliability, accuracy, and operational simplicity—this UHPLC system delivers consistent and reproducible separation performance with an intuitive user experience and fully biocompatible fluidics. It seamlessly integrates with Chromeleon™ Chromatography Data System (CDS) for powerful method control, data processing, and regulatory compliance.
Key Performance Advantages
1. Flexible Quaternary & Binary Solvent Blending
- Supports 4-channel low-pressure quaternary solvent mixing
- Up to 6-channel high-pressure binary mixing (with binary configuration)
- Ideal for method development, method transfer, and gradient optimization
- SmartFlow™ pumping technology adjusts for solvent compressibility, ensuring precise flow and gradient delivery
Pump performance:
- 1000 bar (15,000 psi) maximum pressure
- Up to 8 mL/min flow rate
2. Advanced Sample Handling with Split Sampler FT
The Vanquish Flex UHPLC includes the Split Sampler FT, providing:
- Unrivaled dosage precision with SmartInject™ technology
- Standard capacity of 216 vials
- Expandable to 8832 samples using the Vanquish Charger module
- Air stream cooling (4°C to 40°C) for sample integrity
- Automated barcode recognition for effortless, error-free workflows
- Minimal carryover for trace analysis
3. Precision Column Temperature Control
The system integrates the Vanquish Column Compartment H, ensuring:
- Two thermostatting modes: Still-air and Forced-air
- Broad temperature range from 5°C to 120°C
- Active eluent preheating and post-column cooling
- Excellent thermal uniformity for consistent retention and peak shape
- Full support for advanced LC workflows with optional switching valves
4. Multiple High-Performance Detection Options
Maximize analytical insight with flexible detector choices:
- Diode Array Detection (DAD) – high sensitivity & spectral purity
- Fluorescence Detection (FLD) – selective trace-level detection
- Charged Aerosol Detection (CAD) – near-universal response for non-UV absorbing analytes
- Mass Spectrometry (MS) connectivity for highest analytical capability
Detectors support fast acquisition rates up to 250 Hz, matching ultrafast UHPLC separations.
5. Seamless Chromeleon™ CDS Integration
- Gold-standard chromatography data system (CDS)
- Full instrument control, sequence handling & intelligence
- 21 CFR Part 11–ready audit trail and compliance tools
- Operational Simplicity™ design for intuitive user experience
6. Reliable, Tool-Free Viper™ Connections
- All fluidic connections use Thermo Scientific™ Viper™ fingertight fittings
- Tool-free, leak-free performance
- Minimizes dead volume & improves peak shapes
- Enhances uptime and ease of maintenance
7. Sustainability & ACT Ecolabel Certification
- Reduced solvent waste
- Energy-efficient design
- Sustainable packaging
- Recognized by My Green Lab ACT Ecolabel for environmental transparency
Applications
- Method development laboratories
- Pharmaceutical & biopharmaceutical QC/R&D
- Environmental analysis
- Food & beverage testing
- Forensic and toxicology workflows
- High-throughput screening
- MS-connected UHPLC workflows
- Research and academic environments
Specifications
| Parameter | Details |
|---|---|
| Description | Vanquish Flex Quaternary UHPLC System |
| Catalog Number | IQLAAAGABHFAPUMBHV |
| Type | Integrated Biocompatible UHPLC System |
| Max Pressure | 100 MPa (1000 bar / 15,000 psi) |
| Solvent Channels | 4 (quaternary mixing) |
| Column Temperature Range | 5°C to 120°C (in 0.1°C increments, 18°C below ambient) |
| Sample Temperature Range | 4°C to 40°C (in 0.1°C increments) |
| Detector Data Rate | Up to 250 Hz |
| Flow Rate Range | Up to 8 mL/min |
| For Use With | Quaternary low-pressure mixing applications |
| Green Features | Less waste, energy-efficient, sustainable packaging |
| Unit Size | Each |
The Thermo Scientific™ Vanquish™ Flex UHPLC System combines biocompatibility, flexible quaternary solvent blending, precision temperature control, high-throughput sample handling, and industry-leading detection capabilities. Designed for method development, routine analysis, and MS connectivity, it delivers unmatched flow precision, sensitivity, and reliability for demanding UHPLC applications.
Brochure: Vanquish HPLC and UHPLC Bibliography : LC That Takes Your Productivity to New Heights
The Thermo Scientific™ Vanquish™ Flex UHPLC System is a state-of-the-art, biocompatible ultra-high performance liquid chromatography (UHPLC) platform engineered to deliver exceptional flexibility, high precision, and robust analytical performance. Designed for method development, high-throughput workflows, and complex applications, the Vanquish Flex system incorporates advanced quaternary or binary solvent blending capabilities, industry-leading pumping technology, precision sample handling, and comprehensive detection options.
Built upon the Vanquish platform’s core values—uptime, reliability, accuracy, and operational simplicity—this UHPLC system delivers consistent and reproducible separation performance with an intuitive user experience and fully biocompatible fluidics. It seamlessly integrates with Chromeleon™ Chromatography Data System (CDS) for powerful method control, data processing, and regulatory compliance.
Key Performance Advantages
1. Flexible Quaternary & Binary Solvent Blending
- Supports 4-channel low-pressure quaternary solvent mixing
- Up to 6-channel high-pressure binary mixing (with binary configuration)
- Ideal for method development, method transfer, and gradient optimization
- SmartFlow™ pumping technology adjusts for solvent compressibility, ensuring precise flow and gradient delivery
Pump performance:
- 1000 bar (15,000 psi) maximum pressure
- Up to 8 mL/min flow rate
2. Advanced Sample Handling with Split Sampler FT
The Vanquish Flex UHPLC includes the Split Sampler FT, providing:
- Unrivaled dosage precision with SmartInject™ technology
- Standard capacity of 216 vials
- Expandable to 8832 samples using the Vanquish Charger module
- Air stream cooling (4°C to 40°C) for sample integrity
- Automated barcode recognition for effortless, error-free workflows
- Minimal carryover for trace analysis
3. Precision Column Temperature Control
The system integrates the Vanquish Column Compartment H, ensuring:
- Two thermostatting modes: Still-air and Forced-air
- Broad temperature range from 5°C to 120°C
- Active eluent preheating and post-column cooling
- Excellent thermal uniformity for consistent retention and peak shape
- Full support for advanced LC workflows with optional switching valves
4. Multiple High-Performance Detection Options
Maximize analytical insight with flexible detector choices:
- Diode Array Detection (DAD) – high sensitivity & spectral purity
- Fluorescence Detection (FLD) – selective trace-level detection
- Charged Aerosol Detection (CAD) – near-universal response for non-UV absorbing analytes
- Mass Spectrometry (MS) connectivity for highest analytical capability
Detectors support fast acquisition rates up to 250 Hz, matching ultrafast UHPLC separations.
5. Seamless Chromeleon™ CDS Integration
- Gold-standard chromatography data system (CDS)
- Full instrument control, sequence handling & intelligence
- 21 CFR Part 11–ready audit trail and compliance tools
- Operational Simplicity™ design for intuitive user experience
6. Reliable, Tool-Free Viper™ Connections
- All fluidic connections use Thermo Scientific™ Viper™ fingertight fittings
- Tool-free, leak-free performance
- Minimizes dead volume & improves peak shapes
- Enhances uptime and ease of maintenance
7. Sustainability & ACT Ecolabel Certification
- Reduced solvent waste
- Energy-efficient design
- Sustainable packaging
- Recognized by My Green Lab ACT Ecolabel for environmental transparency
Applications
- Method development laboratories
- Pharmaceutical & biopharmaceutical QC/R&D
- Environmental analysis
- Food & beverage testing
- Forensic and toxicology workflows
- High-throughput screening
- MS-connected UHPLC workflows
- Research and academic environments
Specifications
| Parameter | Details |
|---|---|
| Description | Vanquish Flex Quaternary UHPLC System |
| Catalog Number | IQLAAAGABHFAPUMBHV |
| Type | Integrated Biocompatible UHPLC System |
| Max Pressure | 100 MPa (1000 bar / 15,000 psi) |
| Solvent Channels | 4 (quaternary mixing) |
| Column Temperature Range | 5°C to 120°C (in 0.1°C increments, 18°C below ambient) |
| Sample Temperature Range | 4°C to 40°C (in 0.1°C increments) |
| Detector Data Rate | Up to 250 Hz |
| Flow Rate Range | Up to 8 mL/min |
| For Use With | Quaternary low-pressure mixing applications |
| Green Features | Less waste, energy-efficient, sustainable packaging |
| Unit Size | Each |
The Thermo Scientific™ Vanquish™ Flex UHPLC System combines biocompatibility, flexible quaternary solvent blending, precision temperature control, high-throughput sample handling, and industry-leading detection capabilities. Designed for method development, routine analysis, and MS connectivity, it delivers unmatched flow precision, sensitivity, and reliability for demanding UHPLC applications.
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