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MASTDISCS® Combi Carba plus for 50 tests
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CARTRIDGE A: Penem discs
CARTRIDGE B: Penem + MβL inhibitor
CARTRIDGE C: Penem + KPC inhibitor
CARTRIDGE D: Penem + AmpC inhibitor
CARTRIDGE E: Temocillin + MβL inhibitor
Specifications:
| Application | Antimicrobial Resistance |
| Storage Temperature | 2-8°C |
| Product Type | Antibiotic Disc |
| Product Brand | MAST |
| Product Grade | Microbiology grade |
Phenotypic Detection of Carbapenemase & OXA-48-like Enzymes in Enterobacterales
The MASTDISCS® Combi Carba Plus is a phenotypic disc diffusion test kit designed for the detection of carbapenemase-producing Enterobacterales, including OXA-48-like enzymes. This EUCAST-compliant kit allows microbiologists to differentiate between major carbapenemase classes, such as Metallo-β-Lactamases (MBL), Klebsiella pneumoniae carbapenemase (KPC), and AmpC-mediated carbapenem resistance.
This five-cartridge system provides an accurate, cost-effective, and easy-to-use method for detecting bacterial resistance to carbapenems, ensuring effective antimicrobial susceptibility testing (AST) and infection control.
Key Features & Benefits
✅ EUCAST-Validated for Carbapenemase Detection – Ensures accurate and reliable results
✅ Five-Cartridge System for Differentiation of Carbapenemase Types – Identifies MBL, KPC, AmpC-mediated resistance, and OXA-48-like enzymes
✅ Rapid & Cost-Effective Phenotypic Testing – Provides clear interpretation for clinical microbiology labs
✅ Ready-to-Use Disc Format – Simplifies workflow and eliminates preparation errors
✅ Essential for Antibiotic Resistance Surveillance & Stewardship – Supports infection control programs in healthcare settings
✅ Optimized for Enterobacterales – Suitable for E. coli, Klebsiella spp., Enterobacter spp., and other carbapenem-resistant organisms
Technical Specifications
| Attribute | Details |
|---|---|
| Product Name | MASTDISCS® Combi Carba Plus |
| Test Format | Disc Diffusion Method |
| Number of Tests | 50 Tests |
| Target Organisms | Enterobacterales (E. coli, Klebsiella spp., Enterobacter spp.) |
| Application | Phenotypic Detection of Carbapenemase Production |
| Storage Conditions | 2–8°C |
| Shelf Life | Refer to product label for expiry date |
| Compliance | EUCAST & CLSI Guidelines for AST |
Cartridge Breakdown & Functionality
| Cartridge | Contents | Purpose |
|---|---|---|
| A | Penem discs | Baseline reference for carbapenem resistance |
| B | Penem + MβL inhibitor | Detects Metallo-β-Lactamase (MBL) production |
| C | Penem + KPC inhibitor | Identifies Klebsiella pneumoniae carbapenemase (KPC) |
| D | Penem + AmpC inhibitor | Differentiates AmpC-mediated carbapenem resistance |
| E | Temocillin + MβL inhibitor | Detects OXA-48-like carbapenemases |
Applications
🦠 Clinical Microbiology & Hospital Laboratories – Identifies carbapenem-resistant Gram-negative bacteria
🔬 Antimicrobial Susceptibility Testing (AST) – Helps guide effective antibiotic selection for patient treatment
⚕ Epidemiological Surveillance & Infection Control – Supports tracking of carbapenemase-producing bacterial strains
🏥 Pharmaceutical & Biopharmaceutical Research – Assesses antibiotic resistance mechanisms for drug development
How to Use the MASTDISCS® Combi Carba Plus Kit
1️⃣ Prepare a standardized bacterial inoculum (0.5 McFarland standard).
2️⃣ Inoculate a Mueller-Hinton agar plate evenly using a sterile swab.
3️⃣ Place all five MASTDISCS® Combi Carba Plus cartridges onto the agar surface.
4️⃣ Incubate at 35–37°C for 16–20 hours.
5️⃣ Measure the zone of inhibition around each disc.
6️⃣ Interpret results based on inhibition patterns according to EUCAST/CLSI guidelines.
Ordering Information
| Pack Size | Catalog Number |
|---|---|
| 50 Tests | D73C |
Regulatory & Safety Information
⚠️ For In Vitro Diagnostic (IVD) Use Only. Not intended for direct therapeutic applications.
⚠️ Handle with Biosafety Precautions. Follow standard laboratory protocols when handling bacterial cultures.
⚠️ Store at 2–8°C to Maintain Reagent Stability.
Why Choose the MASTDISCS® Combi Carba Plus Kit?
🔹 EUCAST-Compliant for Reliable Detection of Carbapenemase-Producing Bacteria
🔹 Five-Cartridge System for Differentiation of Carbapenemase Mechanisms
🔹 Ready-to-Use Disc Format for Easy & Reliable Laboratory Workflow
🔹 High Sensitivity & Specificity for Carbapenemase Resistance Testing
🔹 Essential for Infection Control & Antimicrobial Stewardship Programs
For bulk orders, technical support, or additional information, contact LabMart Limited today. 🚀