Liofilchem® Carbenicillin CAR Antimicrobial Susceptibility Discs, 100 µg

Liofilchem® Carbenicillin Discs (100 µg) are ready-to-use, high-quality antimicrobial susceptibility testing (AST) discs designed for use in the Kirby-Bauer disk diffusion method on Mueller-Hinton agar. Each disc is impregnated with 100 µg of Carbenicillin, a broad-spectrum beta-lactam antibiotic belonging to the carboxypenicillin group. These discs are manufactured under strict quality control to comply with ISO 9001 and ISO 13485 standards.

Key Features

• High precision content: Each disc contains exactly 100 µg of Carbenicillin.
• Validated performance: Compliant with CLSI and EUCAST standards for susceptibility testing.
• Sterile and ready to use: Individually packaged or in cartridges to maintain sterility and ease of handling.
• Long shelf-life: Stable under recommended storage conditions.
• Color-coded labels: For easy identification of antibiotic type and potency.

Applications and Use Cases

1. Clinical Microbiology

Used in hospital and diagnostic labs to:

• Determine the susceptibility of Pseudomonas aeruginosa, Proteus spp., and Escherichia coli strains.
• Guide the selection of effective antibiotic treatment for patients with urinary tract infections (UTIs), septicemia, and respiratory tract infections.

2. Pharmaceutical Quality Control

• Evaluate the antimicrobial effectiveness of Carbenicillin formulations.
• Support batch release testing in antibiotic production.

3. Research and Development

• Study resistance patterns and mechanisms in gram-negative bacteria.
• Screen environmental and clinical isolates for emerging resistance trends.
• Investigate synergistic effects in combination therapy studies.

Use Instructions

1. Prepare Mueller-Hinton agar plates.
2. Inoculate plates with a standardized bacterial suspension (e.g., 0.5 McFarland).
3. Apply the Carbenicillin disc (100 µg) using sterile forceps or an automatic disc dispenser.
4. Incubate plates at 35 ± 2 °C for 16–18 hours.
5. Measure the diameter of the zone of inhibition in mm.
6. Interpret results according to CLSI or EUCAST guidelines.

Storage and Shelf Life

• Storage temperature: 2–8°C
• Shelf life: Typically 2–3 years from manufacturing date when unopened and stored appropriately.

Liofilchem® Carbenicillin CAR Discs (100 µg) are essential tools in microbiological diagnostics and research. They support reliable susceptibility profiling of clinically relevant bacteria, enabling informed therapeutic decisions and advancing antimicrobial stewardship programs. Their precision, stability, and compliance with global standards make them a dependable choice for routine laboratory use.