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VWR Trifluoroacetic acid 100%, HiPerSolv CHROMANORM® for HPLC
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Packaged under nitrogen.
Formula: C₂HF₃O₂
CAS Number: 76-05-1
Specifications:
| Application | HPLC | ||
| Storage Temperature | Ambient | ||
| Product Type | Laboratory Chemical | Forms | Liquid |
| Product Brand | VWR | ||
| Product Grade | HPLC Grade | Formula | C₂HF₃O₂ |
VWR Trifluoroacetic Acid (TFA, C₂HF₃O₂) is a high-purity, volatile organic acid with an assay of ≥99.80%, optimized for high-performance liquid chromatography (HPLC) and other trace-level analytical techniques. This HiPerSolv CHROMANORM® grade product is filtered and packaged under nitrogen to ensure low UV absorbance, exceptional purity, and stability.
It is widely used as a mobile phase modifier, ion-pairing agent, and acidifying component in reversed-phase HPLC methods. Its high volatility and compatibility with mass spectrometry make it particularly useful in LC-MS workflows.
Product Specifications
| Property | Value |
|---|---|
| Product Name | Trifluoroacetic Acid (TFA) |
| Grade | HiPerSolv CHROMANORM® for HPLC |
| Chemical Formula | C₂HF₃O₂ |
| Molecular Weight | 114.02 g/mol |
| CAS Number | 76-05-1 |
| MDL Number | MFCD00004169 |
| Merck Index | 13,09754 |
| EINECS Number | 200-929-3 |
| UN Number | UN2699 |
| ADR Classification | Class 8 (Corrosive), Packing Group I |
| GHS Classification | GHS05 (Corrosive), GHS07 (Irritant) |
| Boiling Point | 71.8 °C |
| Melting Point | –15 °C |
| Density (20 °C) | 1.490 g/cm³ |
| Storage Temperature | Ambient |
| Packaging Conditions | Packaged under nitrogen |
| Colour Value | Max. 10 APHA |
| Non-Volatile Matter | Max. 0.005% |
| UV Transmittance @ 210 nm | ≥30% |
| UV Transmittance @ 220 nm | ≥60% |
| UV Transmittance @ 230 nm | ≥85% |
| UV Transmittance @ 240 nm | ≥95% |
| UV Transmittance @ 250 nm | ≥99% |
Packaging
| Catalog Number | Pack Type | Pack Size |
|---|---|---|
| 153112E | Glass bottle | 100 mL |
Applications
- Mobile phase modifier in reversed-phase HPLC
- Ion-pairing reagent for peptide and protein separation
- Volatile acid for LC-MS compatibility
- Acidifying agent in analytical buffers and eluents
- Sample preparation for trace-level detection and mass spectrometry
- Used in pharmaceutical, biochemical, and environmental analysis
Safety and Handling
- Corrosive – causes severe skin burns and eye damage
- Irritant – vapors may cause respiratory irritation
- Use only in well-ventilated areas or fume hoods
- Wear chemical-resistant gloves, goggles, and lab coat
- Store in tightly sealed container, protected from moisture and light
- Refer to the SDS for complete safety, handling, and disposal guidance
VWR Trifluoroacetic Acid 100%, HiPerSolv CHROMANORM® is a high-performance reagent for chromatographers and analytical chemists who demand exceptional UV transparency, consistency, and LC-MS compatibility. Its purity and low non-volatile residue make it ideal for sensitive and regulated analytical workflows.