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The Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System is a state-of-the-art tandem mass spectrometry platform designed for ultra-sensitive quantitative analysis, regulatory compliance, and high-throughput laboratory workflows. Combining Thermo Scientific’s advanced triple quadrupole technology, innovative NeverVent™ maintenance capability, and powerful Chromeleon™ Chromatography Data System (CDS) software, the TSQ 9610 delivers exceptional sensitivity, robustness, and productivity.
Equipped with the ExtractaBrite™ Electron Ionization (EI) source, extended linear dynamic range detection, and rapid Selected Reaction Monitoring (SRM), the TSQ 9610 ensures precise quantification of trace-level compounds even in complex sample matrices. This makes it ideal for environmental testing, food safety, pharmaceutical analysis, forensic toxicology, and petrochemical applications.
The TSQ 9610 is engineered to maximize uptime, minimize maintenance interruptions, and accelerate return on investment, making it a trusted solution for laboratories requiring reliable, regulatory-compliant GC-MS/MS performance.
Key Features and Advantages
Exceptional Sensitivity and Quantitative Accuracy
- Advanced triple quadrupole mass analyzer for ultra-trace detection
- Extended linear dynamic range exceeding 10⁷, ensuring accurate quantitation across wide concentration ranges
- Rapid SRM acquisition with >800 SRM transitions per second
- Excellent signal-to-noise ratio for reliable low-level detection
ExtractaBrite™ Electron Ionization Source
- Wireless EI source with inert, non-coated construction
- Programmable up to 350°C to minimize contamination
- Dual filaments ensure extended operational lifetime
- Cartridge-based design allows rapid removal and cleaning
NeverVent™ Technology for Maximum Uptime
- Enables ion source cleaning without venting the mass spectrometer
- Reduces downtime and increases laboratory productivity
- Allows GC column replacement without interrupting workflows
High-Speed and High-Resolution Performance
- Mass range: 1.2 to 1100 amu
- Resolution: ≤ 1.0 amu across entire mass range
- Fast scanning speed: up to 20,000 u/sec
- Acquisition rate: >97 scans/sec
XLXR™ Detection System for Superior Sensitivity
- Off-axis detection with 10 kV dynode for enhanced signal integrity
- Dynamic range exceeding 10⁹
- Digital noise discrimination for improved detection limits
- Linear output up to 115 μA
Intelligent Software and Workflow Automation
- Fully integrated with Thermo Scientific™ Chromeleon™ CDS
- SmartStatus™ monitoring for instrument readiness and maintenance alerts
- Automated workflows reduce operator intervention
- Simplified method setup and faster deployment
Advanced Scan Modes
The TSQ 9610 supports comprehensive scan capabilities:
MS Mode
- Full Scan (FS)
- Selected Ion Monitoring (SIM)
- Timed SIM (t-SIM)
- Simultaneous FS/SIM
MS/MS Mode
- Selected Reaction Monitoring (SRM)
- Timed SRM (t-SRM)
- Full Scan/SRM simultaneous
Advanced Structural Analysis Modes
- Product ion scan
- Precursor ion scan
- Neutral loss scan
Technical Specifications
| Parameter | Specification |
|---|---|
| Instrument Type | Triple Quadrupole GC-MS/MS |
| Ion Source | ExtractaBrite™ Electron Ionization (EI) |
| Mass Range | 1.2–1100 amu |
| Resolution | ≤ 1.0 amu |
| Scan Speed | Up to 20,000 u/sec |
| SRM Speed | >800 SRM transitions/sec |
| Acquisition Rate | >97 scans/sec |
| Dynamic Range | >10⁹ |
| Linear Range | >10⁷ |
| Collision Energy Range | 0–60 eV |
| Source Temperature | Up to 350°C |
| Vacuum Pump | 240 L/s turbomolecular pump |
| Detector | XLXR™ detection system |
| Software | Chromeleon™ CDS compatible |
Applications
The TSQ 9610 GC-MS/MS system is ideal for:
- Environmental monitoring (pesticides, pollutants, VOCs, SVOCs)
- Food safety testing (residues, contaminants, additives)
- Pharmaceutical impurity and residual solvent analysis
- Clinical and forensic toxicology
- Petrochemical and hydrocarbon analysis
- Cannabis and natural product testing
- Industrial quality control
Unique Advantages
- Ultra-sensitive detection for trace-level compounds
- Exceptional uptime with NeverVent™ maintenance technology
- High SRM capacity for multi-compound analysis
- Robust performance in complex matrices
- Fast return on investment through increased productivity
- Ideal for high-throughput laboratories and regulatory environments
The Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System delivers industry-leading sensitivity, robustness, and productivity for demanding analytical laboratories. Its advanced triple quadrupole design, ExtractaBrite™ ion source, and NeverVent™ maintenance capability ensure reliable, high-confidence quantitative analysis with minimal downtime. This system is an ideal solution for environmental, pharmaceutical, food safety, forensic, and industrial laboratories requiring ultra-sensitive GC-MS/MS performance.
Brochure: TSQ 9610 Triple Quadrupole GC-MS/MS System
Case Study: Increased Laboratory Efficiency with the TSQ 9610 GC-MS/MS in a Food and Environmental Analytical Laboratory
NeverVent technology, change and clean ion sources without venting the mass spectrometer.
TSQ 9610 Mass Spectrometers User Guide
The Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System is a state-of-the-art tandem mass spectrometry platform designed for ultra-sensitive quantitative analysis, regulatory compliance, and high-throughput laboratory workflows. Combining Thermo Scientific’s advanced triple quadrupole technology, innovative NeverVent™ maintenance capability, and powerful Chromeleon™ Chromatography Data System (CDS) software, the TSQ 9610 delivers exceptional sensitivity, robustness, and productivity.
Equipped with the ExtractaBrite™ Electron Ionization (EI) source, extended linear dynamic range detection, and rapid Selected Reaction Monitoring (SRM), the TSQ 9610 ensures precise quantification of trace-level compounds even in complex sample matrices. This makes it ideal for environmental testing, food safety, pharmaceutical analysis, forensic toxicology, and petrochemical applications.
The TSQ 9610 is engineered to maximize uptime, minimize maintenance interruptions, and accelerate return on investment, making it a trusted solution for laboratories requiring reliable, regulatory-compliant GC-MS/MS performance.
Key Features and Advantages
Exceptional Sensitivity and Quantitative Accuracy
- Advanced triple quadrupole mass analyzer for ultra-trace detection
- Extended linear dynamic range exceeding 10⁷, ensuring accurate quantitation across wide concentration ranges
- Rapid SRM acquisition with >800 SRM transitions per second
- Excellent signal-to-noise ratio for reliable low-level detection
ExtractaBrite™ Electron Ionization Source
- Wireless EI source with inert, non-coated construction
- Programmable up to 350°C to minimize contamination
- Dual filaments ensure extended operational lifetime
- Cartridge-based design allows rapid removal and cleaning
NeverVent™ Technology for Maximum Uptime
- Enables ion source cleaning without venting the mass spectrometer
- Reduces downtime and increases laboratory productivity
- Allows GC column replacement without interrupting workflows
High-Speed and High-Resolution Performance
- Mass range: 1.2 to 1100 amu
- Resolution: ≤ 1.0 amu across entire mass range
- Fast scanning speed: up to 20,000 u/sec
- Acquisition rate: >97 scans/sec
XLXR™ Detection System for Superior Sensitivity
- Off-axis detection with 10 kV dynode for enhanced signal integrity
- Dynamic range exceeding 10⁹
- Digital noise discrimination for improved detection limits
- Linear output up to 115 μA
Intelligent Software and Workflow Automation
- Fully integrated with Thermo Scientific™ Chromeleon™ CDS
- SmartStatus™ monitoring for instrument readiness and maintenance alerts
- Automated workflows reduce operator intervention
- Simplified method setup and faster deployment
Advanced Scan Modes
The TSQ 9610 supports comprehensive scan capabilities:
MS Mode
- Full Scan (FS)
- Selected Ion Monitoring (SIM)
- Timed SIM (t-SIM)
- Simultaneous FS/SIM
MS/MS Mode
- Selected Reaction Monitoring (SRM)
- Timed SRM (t-SRM)
- Full Scan/SRM simultaneous
Advanced Structural Analysis Modes
- Product ion scan
- Precursor ion scan
- Neutral loss scan
Technical Specifications
| Parameter | Specification |
|---|---|
| Instrument Type | Triple Quadrupole GC-MS/MS |
| Ion Source | ExtractaBrite™ Electron Ionization (EI) |
| Mass Range | 1.2–1100 amu |
| Resolution | ≤ 1.0 amu |
| Scan Speed | Up to 20,000 u/sec |
| SRM Speed | >800 SRM transitions/sec |
| Acquisition Rate | >97 scans/sec |
| Dynamic Range | >10⁹ |
| Linear Range | >10⁷ |
| Collision Energy Range | 0–60 eV |
| Source Temperature | Up to 350°C |
| Vacuum Pump | 240 L/s turbomolecular pump |
| Detector | XLXR™ detection system |
| Software | Chromeleon™ CDS compatible |
Applications
The TSQ 9610 GC-MS/MS system is ideal for:
- Environmental monitoring (pesticides, pollutants, VOCs, SVOCs)
- Food safety testing (residues, contaminants, additives)
- Pharmaceutical impurity and residual solvent analysis
- Clinical and forensic toxicology
- Petrochemical and hydrocarbon analysis
- Cannabis and natural product testing
- Industrial quality control
Unique Advantages
- Ultra-sensitive detection for trace-level compounds
- Exceptional uptime with NeverVent™ maintenance technology
- High SRM capacity for multi-compound analysis
- Robust performance in complex matrices
- Fast return on investment through increased productivity
- Ideal for high-throughput laboratories and regulatory environments
The Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System delivers industry-leading sensitivity, robustness, and productivity for demanding analytical laboratories. Its advanced triple quadrupole design, ExtractaBrite™ ion source, and NeverVent™ maintenance capability ensure reliable, high-confidence quantitative analysis with minimal downtime. This system is an ideal solution for environmental, pharmaceutical, food safety, forensic, and industrial laboratories requiring ultra-sensitive GC-MS/MS performance.
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