Thermo Scientific™ Dextran sulphate sodium salt, M.W. ~ 40,000

Thermo Scientific™ Dextran Sulfate Sodium (DSS) Salt is a high-purity, polyanionic derivative of dextran used extensively in biomedical and clinical research. DSS is produced by esterification of dextran with chlorosulfonic acid, yielding a sodium salt form that is freely soluble in water and salt solutions, forming a stable, clear solution.

This M.W. ~40,000 dextran sulfate sodium salt is widely recognized as a reliable reagent for inducing experimental colitis in laboratory animals, making it an essential tool for Inflammatory Bowel Disease (IBD) research. Additionally, DSS has applications in antiviral research and as a biochemical reagent for nucleic acid hybridization and protein stabilization.

Key Features & Benefits

✅ M.W. ~40,000 – Optimal molecular weight for colitis induction models

✅ Sulfur Content ~17% – Corresponds to 1.9 sulfate groups per glucosyl residue

✅ Highly Soluble & Stable – Freely dissolves in water and salt solutions

✅ Reliable IBD Model Agent – Induces spontaneous colitis in animal studies

✅ Versatile Biomedical Applications – Used in antiviral studies, nucleic acid research, and more

✅ Proven Research Reagent – Widely cited in colitis, cancer, and gastrointestinal research

Applications

🔬 Inflammatory Bowel Disease (IBD) Research – DSS-induced colitis model mimics human ulcerative colitis

🦠 Colitis-Associated Cancer (CAC) Studies – Evaluates therapeutic interventions for IBD-related cancers

🧬 Antiviral Research – Investigates DSS as a potential antiviral agent

🛠️ Nucleic Acid Hybridization – Used in biochemical applications for DNA and RNA studies

⚗️ Protein Stabilization & Biochemical Research – Serves as a polyanionic stabilizing agent

Product Specifications

Usage Guidelines

• For Colitis Induction in Animal Models:
  • Oral administration via drinking water in mice induces spontaneous colitis
  • Commonly used in preclinical studies of IBD treatments
• For Biochemical Applications:
  • Dissolves easily in aqueous solutions for nucleic acid hybridization
  • Used as a polyanionic reagent in various molecular biology assays

Regulatory & Safety Information

⚠️ For Research Use Only. Not intended for diagnostic, therapeutic, or human/animal consumption.

• Use in a well-ventilated laboratory with appropriate safety precautions
• Refer to the Safety Data Sheet (SDS) for handling and disposal guidelines

Why Choose Thermo Scientific™ Dextran Sulfate Sodium Salt?

🔹 Optimized for IBD & Colitis Research – Proven reagent for colitis modeling

🔹 High Purity & Reproducibility – Ensures consistent experimental results

🔹 Broad Biomedical Applications – Used in virology, molecular biology, and inflammation research

🔹 Reliable Supply & Packaging – Available in multiple sizes to suit research needs

For bulk orders, technical support, or additional information, contact LabMart Limited today.