Thermo Scientific™ Triphenylphosphine 99%

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Specifications:
Application Organic Synthesis
Storage Temperature Ambient
Product Type Laboratory Chemical Forms Powder
Product Brand Thermo Fisher Scientific™, thermo Scientific
Product Grade Analytical grade Formula C₁₈H₁₅P

Thermo Scientific™ Triphenylphosphine (TPP) is a high-purity organophosphorus compound widely used as a ligand in coordination chemistry, reagent in organic synthesis, and catalyst component in metal-catalyzed transformations. Its trivalent phosphorus atom bonded to three phenyl groups makes it a versatile electron-donating ligand and a nucleophilic reagent in several important chemical reactions.

Key Features

  • High Purity (≥99%) – GC purity ≥98.5% ensures consistent performance in sensitive reactions
  • Reagent-Grade Solid – Supplied as white crystalline powder or flakes
  • Widely Used Ligand – Popular in homogeneous catalysis, especially palladium and rhodium complexes
  • Thermal Stability – High melting (78.5–81.5 °C) and boiling point (377 °C)
  • Available in Scalable Pack Sizes – 25 g to 5 kg packaging for lab to industrial-scale applications

Chemical & Physical Properties

PropertySpecification
Chemical NameTriphenylphosphine
CAS Number603-35-0
FormulaC₁₈H₁₅P
Molecular Weight262.29 g/mol
AppearanceWhite crystalline powder, crystals, or flakes
Melting Point78.5–81.5 °C
Boiling Point377 °C (760 mmHg)
Density1.194 g/cm³ (at 20 °C)
Flash Point181 °C
Storage TemperatureAmbient
Hazard SymbolsGHS07 (Irritant), GHS08 (Health Hazard)

Applications

  • Homogeneous Catalysis – Ligand in palladium-catalyzed reactions (e.g., Suzuki, Heck, Stille couplings)
  • Wittig Reactions – Precursor for phosphonium salts used in olefination of aldehydes and ketones
  • Reagent in Reductive Processes – Triphenylphosphine oxide formation in Mitsunobu reactions
  • Coordination Chemistry – Forms complexes with transition metals for material and catalyst design
  • Pharmaceutical Chemistry – Involved in API synthesis, drug intermediates, and chiral ligands

Ordering Information

Catalog #Pack SizePackaging
14042025025 gPlastic bottle
140422500250 gPlastic bottle
1404200101 kgPlastic bottle
1404200505 kgPlastic drum


Thermo Scientific™ Triphenylphosphine, 99% is a high-performance ligand and synthesis reagent that meets the needs of academic, pharmaceutical, and industrial chemists. With excellent thermal stability and reactivity, it is a fundamental component in modern organometallic and synthetic chemistry.

  • Pack Size:   250g 1kg 5kg 25g
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