Thermo Scientific™ Thiourea 99%, Extra Pure

Thiourea (also known as thiocarbamide) is a high-purity, sulfur-containing organic compound that is structurally related to urea, with the oxygen replaced by a sulfur atom. Supplied at 99% purity, this extra pure grade is ideal for biochemical, analytical, and synthetic chemistry applications.

Thermo Scientific™ Thiourea is widely used as a denaturant in lysis buffers, a protein solubilization agent, an antioxidant, and a chromophore in analytical studies. It also serves roles in redox biology, autophagy research, and aging models, and has notable use in nitrification inhibition, fluorescence sensing, and metal ion complexation.

Key Features & Benefits

• High Purity (≥99%)
  Suitable for research, biochemical, and analytical applications.
• Protein Denaturant & Solubilizer
  Commonly used in lysis buffers to disrupt protein tertiary structure.
• Redox-Active Molecule
  Investigated for its role in oxidative stress, antioxidant defense, and cellular signaling.
• Chromophore and Metal Complexing Agent
  Applied in fluorescence sensor design and analytical detection of metal ions.
• Stable, Crystalline Form
  Easy to handle and store in laboratory conditions.

Chemical Identity & Properties

Applications

• Biochemistry & Molecular Biology
  • Solubilization of proteins in sample preparation buffers
  • Redox agent for oxidative stress assays
• Cellular & Aging Studies
  • Studied for impact on autophagy, aging, and mitochondrial function
• Environmental & Water Chemistry
  • Inhibitor in biological nitrification processes
• Chemical Sensing
  • Ligand component in metal ion sensors (e.g., Ga³⁺ detection)
• Synthetic Chemistry
  • Intermediate for synthesis of heterocycles, thioamides, and pharmaceuticals

References

• Wang et al., Water Sci. Technol. (2017), 75(12), 2900–2907 – Nitrification inhibition
• Park et al., J. Fluoresc. (2020), 30(6), 1457–1462 – Thiourea-based fluorescent Ga³⁺ sensors

Thermo Scientific™ Thiourea, 99%, Extra Pure is a versatile reagent for use in protein biochemistry, cell signaling research, analytical chemistry, and synthetic organic transformations. Its high purity and reactivity make it a reliable component for labs engaged in redox biology, fluorescent sensor development, or environmental chemical studies.