Thermo Scientific™ ß-Nicotinamide adenine dinucleotide phosphate tetrasodium salt hydrate (NADPH-Na4 hydrate, reduced form) 96%, Extra Pure

Specifications:

Description:

β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt Hydrate (NADPH-Na4 Hydrate, Reduced Form) is an essential coenzyme in biochemical reactions, particularly in oxidation-reduction processes. NADPH is involved in a variety of metabolic pathways, including biosynthetic reactions and the detoxification of reactive oxygen species. It plays a critical role in the reduction of NADP+ to NADPH in cellular metabolism, essential for cellular biosynthesis and antioxidant defense.

This product is extra pure (96%) and comes as a white to light yellow powder that is commonly used in enzyme assays, cellular studies, and metabolic research. The product is typically stored in a freezer to maintain its stability and activity.

Key Features:

• High Purity: This NADPH product has a high purity of ≥95% as determined by HPLC, ensuring reliable results in sensitive experiments.
• Low Water Content: The water content is kept to a minimum (≤8%), which is essential for maintaining the chemical integrity and reactivity of the compound.
• Stable Form: It is provided as a tetrasodium salt hydrate, making it stable and suitable for use in a variety of biochemical and cell biology applications.
• Infrared Spectrum: Conforms to expected standards, ensuring the product’s authenticity and quality.

Applications:

1. Biochemical Assays:
   • Used as a coenzyme in enzyme assays, NADPH is essential for studying oxidative phosphorylation and energy metabolism.
2. Cellular Metabolism Studies:
   • Plays a significant role in cellular metabolic pathways, especially in biosynthetic reactions and antioxidant protection.
3. Protein Synthesis and DNA/RNA Repair:
   • Involved in processes such as protein synthesis, lipid metabolism, and DNA/RNA repair, making it an important tool in molecular biology.
4. Research on Reactive Oxygen Species (ROS):
   • NADPH is critical for neutralizing reactive oxygen species and supporting antioxidant defense mechanisms, making it useful in oxidative stress studies.
5. Pharmacological and Medical Research:
   • Often used in drug discovery, particularly when studying enzymes that utilize NADPH as a cofactor, such as those involved in biosynthetic pathways.

Packaging:

Storage:

• Storage Temperature: Store the product at ambient temperature for short-term handling and at -20°C for long-term storage to ensure stability and prevent degradation.

β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt Hydrate (NADPH-Na4) is a versatile and critical biochemical reagent used in various research applications, from enzyme assays and cellular studies to oxidative stress investigations. Its high purity and stable form make it ideal for sensitive and reliable experimental work in biochemistry, pharmacology, and molecular biology.