Thermo Scientific™ 2-Chlorophenyl cyclopentyl ketone, 97%

2-Chlorophenyl Cyclopentyl Ketone (IUPAC: (2-chlorophenyl)(cyclopentyl)methanone) is a synthetic ketone compound used extensively as a pharmaceutical intermediate and synthetic reagent. This compound is particularly significant as an intermediate in the synthesis of ketamine analogues and is also applied in the development of bicyclic and polycyclic aromatic hydrocarbons.

With a GC-assayed purity of >96.0%, this reagent-grade compound is ideal for use in medicinal chemistry, organic synthesis, and SAR (structure-activity relationship) studies in anesthetic drug development.

Key Features & Benefits

• High chemical purity (>96% GC) ensures suitability for organic and medicinal synthesis workflows
• Used as an intermediate in ketamine synthesis and related anesthetic compounds
• Plays a role in the preparation of fused aromatic hydrocarbon systems
• Supplied as a clear, colorless to yellow liquid, ready for reaction setups

Applications

• Pharmaceutical intermediate in the synthesis of ketamine and derivatives
• SAR exploration in short-acting anesthetic analogues
• Reagent in aromatic hydrocarbon ring construction
• Custom molecule development in CNS-active compound research
• Drug metabolism pathway studies involving CYP2B6-mediated demethylation

For Research Use Only. Not for use in diagnostic or therapeutic applications.

Chemical & Physical Properties

Ordering Information

References

• Li et al. Drug Metab. Dispos. 2013 – CYP2B6*6 effect on ketamine metabolism
• Jose et al. Bioorg. Med. Chem. 2013 – Ketamine ester analogues in anesthesia

Thermo Scientific™ 2-Chlorophenyl Cyclopentyl Ketone is a high-purity intermediate ideal for advanced organic synthesis and pharmaceutical R&D, particularly in the field of CNS-active compounds and anesthetic agents. Its role as a precursor in ketamine and polyaromatic structure development makes it valuable in both academic and commercial research labs.